BIOMEDICAL RESEARCH AT BARRY UNIVERSITY

巴里大学是一家为少数族裔服务的机构，该申请寻求MBRS评分计划的支持，以开展生物医学研究项目，以揭开进一步了解疾病过程的机制；调查包含在本申请的四个子项目中。MBRS评分计划有几个目标需要实现。第一个目标与教师研究有关。其中两名研究人员正在研究阿尔茨海默病的不同方面；乔治·费舍尔博士从生化角度研究脑组织中氨基酸的变化，另一名研究人员劳拉·穆德博士来自组织培养研究，研究不同生长因子对阿尔茨海默病脑细胞的影响。第三位研究人员Peter Lin博士研究促性腺激素控制基本生殖的分子机制，这可能适用于人类月经功能障碍。第四位研究员格希尔德·帕克特博士研究了果蝇中的同源异型突变，这将有助于进一步了解人类的遗传疾病和恶性肿瘤。该计划的第二个目标是加强和提高研究人员个人的研究效率。实现这一目标将部分通过对设备、研究人员和教师释放时间的支持，以及通过与其他机构的研究人员的合作互动来实现。预计所有调查人员将提高经评审的出版效率，每年将总共发表四篇论文；此外，所有调查人员将在该计划的第三年向其他机构申请外部资金。第三个目标是提供一个强有力的研究环境，作为对巴里大学崛起倡议的补充。这一目标包括至少增加两名教员，一名有补充申请，另一名有试点项目。这一目标的实现将通过RISE计划为学生发展提供的研究机会来衡量。

This application from Barry University, a minority serving institution, seeks support from the MBRS SCORE program to pursue biomedical research projects to unravel mechanisms that will further the understanding of the disease process; the investigations are contained in four subprojects of this application. There are several goals of the MBRS SCORE program to be accomplished. The first goal relates to faculty research. Two of the investigators are studying differing aspects of Alzheimer's disease; Dr. George Fisher, from a biochemical perspective of altered amino acids in brain tissue and the other, Dr. Laura Mudd, from a tissue culture investigation of the effect of differing growth factors on brain cells effected by Alzheimer's disease. A third investigator, Dr. Peter Lin studies molecular mechanisms by which gonadotropins control basic reproduction which may apply to human menstrual dysfunction. The fourth investigator, Dr. Gerhild Packert, studies homeotic mutations in Drosophila which will lead to a further understanding of genetic disorders and malignancies in humans. The second goal of the program is to strengthen and increase the research productivity of the individual investigators. Reaching this goal will be accomplished, in part, with support for equipment, research personnel and faculty release time and through collaborative interaction with investigators at other institutions. It is anticipated that all investigators will increased refereed publication productivity, and there will be a total of four papers published per year; additionally all investigators will apply for outside funding from other agencies in the third year of this program. The third goal is to provide a strong research environment as a complement for the Barry University RISE initiative. Included in this goal will be the addition of at least two faculty, one with a supplemental application and one with a pilot project. Attainment of this goal will be measured by the research opportunities available for student development with the RISE program.