MOLECULAR APPROACHES TO PEDIATRIC SCIENCE - CHRC

这是少年儿童的竞技续签申请 费城医院(CHOP)MAP/CHRC Grant。在过去的授予期间 期间，我们支持了16个图谱的分子研究培训和研究 从儿科研究员过渡到教职员工的学者 任命(总共有24年的资金)。在准备之日 在这份续签申请(11/96)中，这16人各自持有一名学者 在儿科就诊，已经有12人 成功获得额外的校外研究支助，包括 2RO1，2 R29，5K08，以及RW Johnson少数民族学院K08同等学历。的 尚未获得额外校外研究资助的4人，3人 5个月前才成为MAPS学者。 我们的MAP/CHRC主要基于印章艾布拉姆森研究 大楼，一个提供13.8万平方英尺湿实验室空间的设施。这个 CHOP MAP/CHRC分子核心在这栋楼里，实验室也在 在28名资深调查人员中有23人将为 我们的地图学者。我们还联系了加州大学 宾夕法尼亚州(宾夕法尼亚州大学)，紧邻印章，用于建立 研究人员--1名在维斯塔尔研究所，2名在休斯研究所，以及 P医学院基础科学系2名。 我们的续订申请需要新的计划开发资金以 支持5个地图学者/年。为了放大它的影响 重要计划，CHOP将放弃所有间接成本回收，并将 将MAP/CHRC支持匹配到为MAPS学者提供的分子核心 用法。此外，与前一个批准期一样，该部 宾夕法尼亚大学的儿科医生将在内部提供 产生的资金将大幅补充MAP/CHRC新计划 发展基金，以使我们能够选择和支持一大批 我们优秀的MAPS奖学金申请者的比例。

This is the competitive renewal application of The Children's Hospital of Philadelphia (CHOP) MAPS/CHRC Grant. During the past granting period, we supported molecular research training and research of 16 MAPS Scholars during their transition from pediatric fellowship to faculty appointments (a total of 24 years on funding). At the date of preparation of this renewal application (11/96), each of these 16 holds an academic appointment in a department of pediatrics, and 12 have already been successful in obtaining additional extramural research support, including 2RO1s, 2 R29s, 5K08s, and a RW Johnson Minority Faculty K08 equivalent. Of the 4 who have not yet received additional extramural research support, 3 became MAPS Scholars only 5 months ago. Our MAPS/CHRC is based largely in the CHOP Abramson Research Building, a facility providing 138,000 square feet of wet lab space. The CHOP MAPS/CHRC Molecular Core is in this building, as are the laboratories of 23 of the 28 Established Investigators who will provide mentoring to our MAPS Scholars. We have also reached out to the University of Pennsylvania (U of P), immediately adjacent to CHOP, for Established Investigators--1 at the Wistar Institute, 2 at the Hughes Institute, and 2 in U of P Medical School basic science departments. Our renewal application requests New Program Development funds to support 5 MAPS Scholars/year. In order to amplify the effects of this important program, CHOP will waive all indirect cost recovery, and will match MAPS/CHRC support to the Molecular Core provided for MAPS Scholar usage. In addition, as during the previous granting period, the Department of Pediatrics of the University of Pennsylvania will provide internally generated funds to substantially supplement MAPS/CHRC New Program Development funds, in order to permit us to select and support a large proportion of our outstanding pool of MAPS Scholarship applicants.