MOTIVATIONAL HIV PREVENTION INTERVENTION FOR YOUNG WOMEN

市中心的异性恋少女是感染艾滋病毒增长最快的人群之一。迫切需要制定和评估针对市中心年轻女性的艾滋病毒预防干预措施。提高女性对改变的准备的干预措施可能更有效。研究支持使用信息-动机-行为技能(IMB)模型降低艾滋病毒风险的干预措施。拟议的研究将修改和定义针对15-19岁市中心妇女的IMB艾滋病毒预防干预措施。为了做到这一点，候选人将获得K01奖项，并由专业的艾滋病毒预防科学家迈克尔·凯里博士作为赞助商。培训将包括跨学科的课程工作和经验，以培养：(A)复杂的数据分析技能；(B)更好地理解与艾滋病毒预防有关的社会心理学、行为和发展理论；(C)在开发、实施和评估临床干预研究方面的专业知识；以及(D)关于市中心高危年轻女性降低艾滋病毒风险的可资助RO1提案。这项培训将应用于对市中心妇女(N=48)进行的小规模试验性前测后测设计。在试验性测试和测试前评估之后，参与者将随机分为IMB干预组或结构相同的健康促进控制组。四个IMB课程将教授教育、动机和行为技能；对照组课程将侧重于适合发展的健康话题(例如营养、压力管理)。从测试后评估和焦点小组中，研究人员将分析数据(随着时间的推移对影响敏感)，以比较组内和组间的测试前和测试后分数，并从定性数据中确定代码和主题。研究结果将被用于制定R01提案，以全面测试修改后的干预措施。这一K01奖项将增强候选人的研究知识和技能，使她成为一名独立的调查员，帮助年轻女性改变危险的性行为，从而降低她们感染艾滋病毒的风险。

Inner-city heterosexual teenage women are among the fastest growing populations acquiring HIV infection. There is an urgent need to develop and evaluate HIV prevention interventions targeted to young inner-city females. Interventions that enhance a woman's readiness to change may be more effective. Research supports interventions for reducing HIV risk using the information-motivation-behavioral skills (IMB) model. The proposed study will modify and define an IMB HIV-prevention intervention for inner-city women ages 15-19 years. To do this, the candidate will pursue a K01 award with an expert HIV prevention scientist, Dr. Michael Carey, as sponsor. Training will consist of interdisciplinary course work and experiences that develop: (a) complex data analysis skills; (b) a greater understanding of social psychology, behavioral, and developmental theories related to HIV prevention; (c) expertise in developing, implementing, and evaluating clinical intervention studies; and (d) a fundable RO1 proposal on HIV risk reduction in inner-city at-risk young women. This training will be applied in a small scale experimental pre-test post-test design with inner-city women (N=48). Following pilot testing and pre-testing assessments, participants will randomized into the IMB intervention or the structurally equivalent health promotion control group. Four IMB sessions will teach educational, motivation, and behavioral skills; the control group sessions will focus on developmentally appropriate health topics (e.g. Nutrition, stress management). From post- test assessments and focus groups, researchers will analyze data, (sensitize to effects over time), to compare pre- and post-test scores within and between groups, and identify codes and themes from qualitative data. Findings will be used to develop an R01 proposal to fully test the modified intervention. This K01 award will enhance the candidate's research knowledge and skills, launching her as an independent investigator helping young women change risky sexual behaviors and thus reduce their risk of HIV infection.