International Conference on Hepatitis B Viruses

描述(申请人提供)：感染乙肝病毒(乙肝病毒) 仍然是一个严重的公共卫生问题，估计有3亿慢性病患者 全球的航空公司。近年来，在以下方面取得了实质性进展 建立复制过程中各个步骤的分子基础 病毒，揭示了它在逆转录病毒中的独特地位。然而，巨大的 实验困难，包括缺乏适当的体内和 实验性的感染系统阻碍了类似的详细分析 感染的早期步骤。这些限制进一步阻碍了 基本了解病毒和宿主之间的复杂相互作用及其 对致病性的影响。这次会议不同于面向临床的会议 会议，旨在聚集研究不同方面的科学家 乙肝病毒和相关动物模型病毒，共同讨论最新 概念和技术上的进步。这次会议是由贝蒂博士组织的 斯拉格尔和迈克尔·罗根多夫，他们得到了一个乙肝病毒专家小组的协助 科学家担任12场讲座和2场海报会议的主席。在……里面 此外，还计划举办一个关于有争议问题的研讨会。会话 主题包括：转录、复制、结构蛋白和 受体；调节蛋白；肝细胞癌；乙肝病毒变异体和 丁型肝炎病毒；以及持久性、发病机制和免疫学。每个人 会议将包括4-8次演讲，从提交的摘要中挑选出来 经各届会议主席同行审议。在以前的传统中 除了出席和介绍本系列会议外， 高级调查人员、研究生和博士后研究员将 特别鼓励参加讲座和张贴海报。乙肝病毒 研究是NIAID研究任务中的一个主要主题，这是 仅此一次的年度乙肝会议。

DESCRIPTION (provided by applicant): Infection with Hepatitis B virus (HBV) is still a serious public health problem, with an estimated 300 million chronic carriers worldwide. In recent years, substantial progress has been made in establishing the molecular basis of individual steps in the replication of the virus, revealing its unique status among retroelements. However, immense experimental difficulties, including the lack of appropriate in vivo and experimental, infection systems, have hampered a similarly detailed analysis of the early steps of infection. The limitations have further hindered the fundamental understanding the complex interplay between virus and host and its effects on pathogenicity. This conference is distinct from clinically oriented meetings, and is intended to gather scientists studying different aspects of HBV and related animal model viruses, for joint discussion of the latest conceptual and technical advances. The meeting is organized by Drs. Betty Slagle and Michael Roggendorf, who are assisted by a panel of expert HBV scientists acting as chairpersons for 12 lecture and 2 poster sessions. In addition, it is planned to have a workshop on controversial issues. Session topics will include: transcription; replication; structural proteins and receptors; regulatory proteins; hepatocellular carcinoma; HBV variants and hepatitis delta virus; and persistence, pathogenesis, and immunology. Each session will comprise 4-8 talks, selected from submitted abstracts that are peer-reviewed by the session chairpersons. In the tradition of previous meetings of this series, in addition to the attendance and presentations by senior investigators, graduate students and postdoctoral fellows will be particularly encouraged to participate in the lecture and poster sessions. HBV research is a major topic in the research mission of NIAID, and this is the only annual HBV meeting of its kind.