FASEB Conference--Chromatin and Transcription

描述(申请人摘要)：本申请申请部分资金 连续第六届FASEB夏季研究会议关于“染色质和 抄本“将于2001年7月7日至12日在#年会议中心举行 科罗拉多州斯诺马斯村。这次非常成功的会议的目标是 促进研究DNA模板化过程的研究人员之间的互动 研究染色质结构和组织的个人。这些学科 正在以快速的步伐一起前进。会议发言人已确认 下面列出了。该领域的新调查人员将被邀请参加。 I.基因调控复合体与染色质的相互作用 组蛋白、核小体和高级结构 生病了。染色质修饰与基因表达 异染色质与基因沉默 五、染色体结构和远距离染色质组织 六、表观遗传和发育调控 染色质的复制和修复 八、转录因子功能 IX.染色质中的高级转录因子复合体 会议的中心议题是染色质和 抄写。染色质的调节影响其他重要的生物 例如，染色质和核之间有重要的联系 结构、染色体组织和细胞周期，特别是与 关于组蛋白修饰的最新发现。此外，还有以下问题 与遗传病相关的基因组稳定性和不稳定性将 将在一次关于发育/表观遗传调控的会议上讨论。时间的选择 2001年会议的地点和地点是富有成效和互动性的理想选择 关于这些快速发展领域的数据的讨论。

DESCRIPTION (APPLICANT'S ABSTRACT): This application requests partial funding for the sixth consecutive FASEB Summer Research Conference on "Chromatin and Transcription," to be held on July 7-12. 2001, at the Conference Center in Snowmass Village, Colorado. The goal of this highly successful meeting is to foster interactions between researchers who study DNA-templated processes with individuals who study chromatin structure and organization. These disciplines are moving together at rapid pace. Speakers are confirmed for the sessions listed below. New investigators to the field will be invited to participate. I. Interactions Between Gene Regulatory Complexes and Chromatin II. Histones, Nucleosomes, and Higher Order Structure Ill. Chromatin Modification and Gene Expression IV. Heterochromatin and Gene Silencing V. Chromosome Structure and Long-Range Chromatin Organization VI. Epigenetic and Developmental Regulation VII. Replication and Repair of Chromatin VIII. Transcription Factor Function IX. Higher Order Transcription Factor Complexes in Chromatin The meeting's central topic is the relationship between chromatin and transcription. The regulation of chromatin impacts other critical biological areas; for instance, there are important links between chromatin and nuclear structure, chromosome organization, and the cell cycle, particularly relating to recent discoveries about histone modification. Moreover, questions of genomic stability and instability, which are relevant to genetic disease, will be addressed in a session on developmental/epigenetic regulation. The timing and location of the 2001 conference are ideal for productive and interactive discussions about data in these rapidly evolving areas.