FASEB Conference--Chromatin and Transcription

描述（申请人摘要）：此申请要求部分资金 连续第六届FASEB夏季研究会议“染色质和 会议将于7月7日至12日举行。2001年，在会议中心， 科罗拉多的斯诺马斯村。这次非常成功的会议的目标是 促进研究DNA模板化过程的研究人员与 研究染色质结构和组织的人。这些学科 正在快速地移动已确认会议发言人 列在下面。将邀请外地新调查员参加。 I.基因调控复合物与染色质的相互作用 二.组蛋白、核小体和高级结构 伊利诺伊州染色质修饰与基因表达 四.异染色质与基因沉默 V.染色体结构和长程染色质组织 六.表观遗传与发育调控 七.染色质的复制与修复 八.转录因子功能 九.染色质中的高阶转录因子复合物 会议的中心议题是染色质与细胞周期的关系。 转录。染色质的调节影响其他重要的生物学特性， 区域;例如，染色质和细胞核之间有重要的联系， 结构、染色体组织和细胞周期，特别是与 最近发现的组蛋白修饰。此外， 基因组的稳定性和不稳定性与遗传疾病有关， 在发育/表观遗传调节会议上讨论。定时 2001年会议的地点是生产和互动的理想场所。 在这些快速发展的领域讨论数据。

DESCRIPTION (APPLICANT'S ABSTRACT): This application requests partial funding for the sixth consecutive FASEB Summer Research Conference on "Chromatin and Transcription," to be held on July 7-12. 2001, at the Conference Center in Snowmass Village, Colorado. The goal of this highly successful meeting is to foster interactions between researchers who study DNA-templated processes with individuals who study chromatin structure and organization. These disciplines are moving together at rapid pace. Speakers are confirmed for the sessions listed below. New investigators to the field will be invited to participate. I. Interactions Between Gene Regulatory Complexes and Chromatin II. Histones, Nucleosomes, and Higher Order Structure Ill. Chromatin Modification and Gene Expression IV. Heterochromatin and Gene Silencing V. Chromosome Structure and Long-Range Chromatin Organization VI. Epigenetic and Developmental Regulation VII. Replication and Repair of Chromatin VIII. Transcription Factor Function IX. Higher Order Transcription Factor Complexes in Chromatin The meeting's central topic is the relationship between chromatin and transcription. The regulation of chromatin impacts other critical biological areas; for instance, there are important links between chromatin and nuclear structure, chromosome organization, and the cell cycle, particularly relating to recent discoveries about histone modification. Moreover, questions of genomic stability and instability, which are relevant to genetic disease, will be addressed in a session on developmental/epigenetic regulation. The timing and location of the 2001 conference are ideal for productive and interactive discussions about data in these rapidly evolving areas.