Conference--Molecular Biology in Orthopaedics

描述：爆炸性进展和由此产生的技术进步 分子生物学在过去的十年中呈现出惊人的潜力 理解和治疗疾病的翻译方法。例如, 肌肉骨骼疾病的巨大流行率和社会成本突显了 分子生物学进展在临床应用中的价值 菲尔德。这次为期3天的研讨会由美国整形外科学会共同主办 外科医生(AAOS)将于2001年9月7日至9日在亚利桑那州斯科茨代尔举行，并将 聚集了一群不同的分子生物学家，骨科临床医生， 和年轻的研究人员，对分子研究感兴趣 肌肉骨骼系统提供相关主题的概述，来自 各种观点，并定义最有希望的未来方向 应用于骨骼组织和骨科的分子生物学研究 临床问题。拟议的研讨会目标包括：1.定义当前的 我国分子生物学的基础、技术和临床应用现状 骨科。2.提供跨学科讨论论坛，以产生 分子生物学在骨科领域的新应用3.引进年轻的骨科医生 研究人员和临床医生对可能加强他们研究的技术的支持。 4.确定基本应用和翻译应用的需求和机会 从分子生物学到骨科。5.明确未来发展方向 与肌肉骨骼系统有关的分子生物学研究。6. 通过联合出版一本书，最大限度地扩大研讨会的影响 AAOS总结了当前的基础、技术和临床知识 分子生物学及骨科未来相关研究方向。 研讨会将试图通过教学研讨会来实现这些目标 专注于新的分子技术、基因组学和基因结构，并特别 关于发育、遗传病、肌肉骨骼肿瘤学、 转基因模型、基因治疗和基因表达调控。 与会者还将讨论与基因表达调控相关的问题 尤其是成骨细胞、破骨细胞、软骨、干细胞和损伤 修理。

DESCRIPTION: The explosive progress and resulting technical advances in molecular biology during the past decade present an astonishing potential for translational approaches to understanding and treating diseases. For example, musculoskeletal disorders' enormous prevalence and societal costs underscore the value of the clinical application of advances in molecular biology to this field. This 3 day workshop co-sponsored by the American Academy of Orthopaedic Surgeons (AAOS) will be held September 7-9, 2001 in Scottsdale, AZ, and will bring together a diverse group of molecular biologists, orthopaedic clinicians, and young investigators with research interests in the molecular study of the musculoskeletal system to provide an overview of the relevant topics from a variety of perspectives and to define the most promising future directions for molecular biological research as applied to skeletal tissues and orthopaedic clinical problems. The proposed workshop goals include: 1. Defining the current status of basic, technical and clinical applications of molecular biology in orthopaedics. 2. Providing a cross-disciplinary discussion forum to generate novel molecular applications to orthopaedics 3. Introducing young orthopaedic investigators and clinicians to technologies that may enhance their research. 4. Defining needs and opportunities for basic and translational applications of molecular biology to orthopaedics. 5. Identifying future directions of molecular biologic research as it relates to the musculoskeletal system. 6. Maximizing impact of the workshop through publication of a book in conjunction with the AAOS summarizing the current basic, technical, and clinical knowledge of molecular biology and future related research directions in orthopaedics. The workshop will attempt to achieve these aims by instructional seminars focusing on new molecular techniques, genomics, and gene structure, and special topic sections on development, genetic diseases, musculoskeletal oncology, transgenic models, gene therapy, and regulation of gene expression. Participants will also discuss regulation of gene expression as it relates specifically to osteoblasts, osteoclasts, cartilage, stem cells, and injury and repair.