IMPACT OF MATERNAL BREAST CANCER ON CHILDREN

母亲乳腺癌对儿童的影响

• 批准号: 6392587
• 负责人: Kathryn Vannatta
• 金额: $ 14.28万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2004-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6392587
• 关键词: adolescence (12-20); age difference; anxiety; behavioral /social science research tag; breast neoplasms; child behavior; child psychology; clinical research; conflict; depression; emotional adjustment; family structure /dynamics; gender difference; human subject; middle childhood (6-11); mother child interaction; outcomes research; peer group; quality of life; questionnaires; self concept; social psychology

The proposed research utilizes the occurrence of a family crisis, diagnosis of a mother's breast cancer (BC), as a naturalistic experiment to evaluate the impact of stressful life events or conditions on the adjustment and well-being of children. BC is selected for study because it is one of the most common forms of cancer and causes of death among women in their child rearing years. Additionally, unlike many other stressful events occurring in the life of a child, the diagnosis of maternal BC is not associated with antecedent psychosocial characteristics of the child, mother, or family. Previous research has suggested that parental physical illness challenges the entire family and may increase the risk of children to experience emotional, social, and behavioral difficulties. Unfortunately, published work in this area is limited by research designs that fail to include appropriate comparison samples and do not obtain relevant data from sources outside the family. Women recently diagnosed with BC who have school-aged children (8-15 years) will be recruited for participation. For each target child whose mother has BC, a same race, same gender, and similar-aged matched classroom comparison peer (MCCP) whose mother does not have cancer will be recruited as a case-control. Identical data will be obtained from multiple sources in children's classrooms (teachers and peers) and families' homes (mother, father, and child) to allow tests of group differences social functioning and emotional well-being. Specific Aim number 1. Compare the social functioning of children whose mothers have been diagnosed with BC to MCCPs. Specific Aim number 2. Compare the emotional well- being of children whose mothers have been diagnosed with BC and MCCPs. Specific Aim number 3. Evaluate whether difficulties in social functioning and emotional well-being evidenced by children of women with BC are mediated by family context variables. Specific Aim number 4. Utilize a case controlled design to evaluate whether the impact of maternal BC on children's social functioning and emotional well-being is moderated by child demographic and disease specific variables. Specific Aim number 5. Collect data regarding family communication about the BC diagnois, treatment, and prognosis in terms of parental beliefs about the value of such information to children and their actual attempts to discuss these factors within the family. Examine associations of cancer-specific communication with broader family context and child outcome variables.

拟议的研究利用家庭危机的发生、母亲乳腺癌（BC）的诊断，作为自然主义实验来评估压力生活事件或条件对儿童适应和福祉的影响。 选择 BC 进行研究是因为它是育儿期妇女中最常见的癌症形式和死亡原因之一。 此外，与儿童生活中发生的许多其他压力事件不同，母亲 BC 的诊断与儿童、母亲或家庭先前的心理社会特征无关。 先前的研究表明，父母的身体疾病会给整个家庭带来挑战，并可能增加孩子经历情感、社交和行为困难的风险。 不幸的是，该领域已发表的工作受到研究设计的限制，这些研究设计未能包括适当的比较样本，也没有从家庭以外的来源获得相关数据。 最近被诊断患有 BC、有学龄儿童（8-15 岁）的女性将被招募参与。 对于母亲患有 BC 的每个目标儿童，将招募母亲未患有癌症的相同种族、相同性别和年龄相近的匹配课堂比较同伴 (MCCP) 作为病例对照。 将从儿童教室（老师和同龄人）和家庭（母亲、父亲和孩子）的多个来源获得相同的数据，以便测试群体差异的社会功能和情感健康。 具体目标 1. 比较母亲被诊断为 BC 的儿童与 MCCP 的社会功能。 具体目标 2：比较母亲被诊断患有 BC 和 MCCP 的孩子的情绪健康状况。 具体目标 3. 评估患有 BC 的妇女的孩子所表现出的社会功能和情感健康方面的困难是否是由家庭环境变量介导的。具体目标 4。利用病例对照设计来评估母亲 BC 对儿童社会功能和情绪健康的影响是否受到儿童人口统计和疾病特定变量的调节。 具体目标 5. 收集有关 BC 诊断、治疗和预后的家庭沟通数据，了解父母对此类信息对儿童价值的信念以及他们在家庭中讨论这些因素的实际尝试。 检查癌症特异性沟通与更广泛的家庭背景和儿童结果变量的关联。