NOVEL, FAST, RELIABLE&INEXPENSIVE RADIATION DOSIMETER

新颖、快速、可靠

• 批准号: 6310476
• 负责人: Gavin James Braithwaite
• 金额: $ 9.86万
• 依托单位: CAMBRIDGE POLYMER GROUP, INC.
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6310476
• 关键词: biomedical equipment development; infrared radiation; ionizing radiation; polyethylenes; polymers; radiation detector; radiation dosage

DESCRIPTION (Applicant's abstract verbatim): In this SBIR phase I proposal, we will develop a new radiation dosimetry technique for use in the ionizing radiation industry. Radiation is frequently used to sterilize biomedical polymers, and improve through crosslinking, the properties of these implants. Polymer irradiation often requires dose levels beyond 200 kGray. Electron beam operators thus need dosimeters with this range and fast response times for on-the-fly dose rate adjustment. Photochromic dyes, the most commonly used dosimetry system, saturate at 50 kGray, often take 5-6 hours to stabilize, and show aging. By making use of the radiolytic reactions in poly(ethylene) undergoing ionizing radiation, a reliable marker for radiation dose can be obtained. Our approach focuses on a specific radiolytic reaction that scales with radiation dose, and is easily measured with infrared absorption. This proposal will involve the design and fabrication of a prototype small enough, and simple enough, to use at a radiation facility with no special training. The thin dosimetry targets will be flexible (and therefore conformable), resilient, tolerant of contamination and damage (therefore ideal for industrial applications in laboratories or on production floors) and will have a response time on the order of minutes. They will also be immune to aging and have considerably higher dosage ranges than other current dosimetry techniques. PROPOSED COMMERCIAL APPLICATION: The proposed dosimeter design will provide a simple, low cost, technique capable of replacing, and improving on, current state-of-the-art radiation dosimetry approaches. The reader will be useable with little or no training. It will therefore be invaluable in any radiation facility that must have fast response dosimeters (such as beam-lines requiring variable doses), in high dose applications (such as orthopaedic implant fabrication), in applications requiring directional irradiation (such as the wire coating industry) and in environments where surface contamination may be an issue.

描述（申请人的逐字摘要）：在这个 SBIR 第一阶段提案中，我们 将开发一种新的辐射剂量测定技术，用于电离 辐射产业。辐射经常用于生物医学灭菌 聚合物，并通过交联改善这些植入物的性能。 聚合物辐照通常需要超过 200 kGray 的剂量水平。电子束 因此，操作员需要具有此范围和快速响应时间的剂量计 动态剂量率调整。最常用的光致变色染料 剂量测定系统，在 50 kGray 饱和，通常需要 5-6 小时才能稳定，并且 显出衰老。利用聚乙烯中的辐射分解反应 接受电离辐射时，辐射剂量的可靠标记可以是 获得。我们的方法侧重于可扩展的特定放射分解反应 与辐射剂量有关，并且可以通过红外吸收轻松测量。这 提案将涉及设计和制造足够小的原型， 而且非常简单，无需特殊培训即可在辐射设施中使用。这 薄的剂量测定目标将是灵活的（因此是顺应的）、有弹性的、 耐污染和损坏（因此非常适合工业 实验室或生产车间的应用）并将得到回应 时间以分钟为单位。他们还将免受衰老影响并具有 比当前其他剂量测定技术高得多的剂量范围。 拟议的商业应用： 所提出的剂量计设计将提供一种简单、低成本的技术，能够 取代并改进当前最先进的辐射剂量测定方法。 读者只需很少的培训或无需培训即可使用。 因此，无论在任何情况下，它都将是无价的 必须具有快速响应剂量计的辐射设施（例如需要的束线） 可变剂量），在高剂量应用（例如整形外科植入物制造）中， 需要定向照射的应用（例如电线涂层行业）和 表面污染可能成为问题的环境。