Internat'l symposium:vascular neuroeffector mechanisms

描述（由申请人提供）：这是一份支持将于2002年7月12日至15日在加利福尼亚州太浩湖Granlibakken会议中心举行的第10届血管神经保护机制国际研讨会的提案。本次会议是第14届世界药理学大会（2002年7月7日至12日，旧金山弗朗西斯科）的卫星会议。这次会议的主要目的是突出神经血管药理学和生理学领域的最新进展。优秀的演讲者将激发对关键主题的讨论，特别强调神经调节机制。这些议题将补充而不是重复世界大会上提出的议题。增加的目标是汇集来自不同国家的科学家，并为年轻科学家提供与更成熟的研究人员互动的机会。会议将为非正式互动提供充分的机会。血管疾病仍然是现代社会中广泛和普遍的发病率和死亡率的来源。多年来持续的研究努力迫使人们不断重新评估基本血管功能和调节理论以及治疗策略。近年来，人们对基本分子机制的理解出现了爆炸式增长。然而，这一知识尚未充分应用于组织、器官和生物体层面的理解。因此，这是一个适当的时机，应用在分子和基因组水平的进展，以进一步了解更完整的血管功能。由于其长期强调神经，血管平滑肌和内皮之间的相互作用，以及专注于临床意义的传统，本次会议是刺激进一步发展的理想场所。会议的亲密和轻松的环境将促进讨论，并使科学家能够巩固在研讨会和世界大会上产生的想法。我们预计，本次会议的各个方面将有助于促进该领域新方向和合作的发展。

DESCRIPTION (provided by applicant): This is a proposal to support the 10th International Symposium on Vascular Neuroettector Mechanisms to be held July 12-15, 2002 in Granlibakken Conference Center, Lake Tahoe, CA. This conference is a satellite of the 14th World Congress of Pharmacology (July 7-12, 2002, San Francisco). The major objective of this conference is to highlight recent progress in the fields of neurovascular pharmacology and physiology. Excellent speakers will stimulate discussion of key topics with particular emphasis on neuroregulator mechanisms. Topics will supplement rather than duplicate those presented at the World Congress. Additions objectives are to bring together scientists from different countries and to provide opportunities for younger scientists to interact with more established investigators. The meeting will provide ample opportunity for informal interaction. Vascular diseases remain a source of extensive and widespread morbidity and mortality in modern society. Sustained investigative efforts over many years have forced continued reevaluation of theories of basic vascular function and regulation as well as therapeutic strategies. Recent years have seen an explosion in understanding of basic molecular mechanisms. However, this knowledge has yet to be fully applied to understanding at the level of tissue, organ and organism. Thus this is an opportune moment to apply advances at the molecular and genomic level to further understanding of more integrated vascular function. With its long history of emphasis on the interactions between nerves, vascular smooth muscle, and the endothelium, and with a tradition of focusing on clinical implications, this conference is an ideal venue for stimulating further advances. The intimate and relaxed setting of the conference will facilitate discussion and allow scientists to consolidate ideas generated at both the symposium and world congress. We anticipate that all aspects of this conference will help to foster development of new directions and collaborations in the field.