Confer. Neural Mechanisms in Cardiovascular Regulation

描述(由申请人提供)：这是一份申请部分资金的FASEB夏季研究会议，主题为“心血管调节中的神经机制”，将于2001年7月20-25日在科罗拉多州的斯诺马斯举行。这次会议将是FASEB关于这一主题的系列会议中的第8次，每2-3年举行一次。神经机制在动脉血压的调节、心肾功能的调节以及病理状态下晕厥、心律失常和猝死的发生等方面起着重要作用。对基础神经机制感兴趣的基础科学家、综合生理学家和对疾病中心血管调节失调机制感兴趣的临床医生都会对这次会议感兴趣。会议的目标是将来自不同科学领域的研究人员和受训人员聚集在一起，在非正式的环境中讨论神经心血管控制的重要方面。FASEB夏季研究会议的独特形式和非正式设置促进了不同学科之间以及受训者和现有研究人员之间的互动。具体目标是：1)由公认的专家和有前途的年轻研究人员提供对神经心血管调节重要领域的最新概述；2)为未来的研究确定新的实验方法和假设；以及3)让大量的受训人员和年轻研究人员参加会议。大约160名与会者将从感兴趣的申请者中挑选出来。大会将包括9个全体会议，每个会议包括4个报告、延长的讨论会议和海报报告。全体会议包括：1)心血管系统的感觉转导机制；2)脑干的神经递质和技术；3)激活RVLM：是什么驱动RVLM血管运动神经元的活动？4)脑在高血压中的作用；5)前脑机制和神经体液控制；6)血压和液体稳态的中枢控制：功能基因组时代；7)高级大脑中心对循环的调节；8)心血管变异性的起源及其功能意义；以及9)交感神经系统在衰老、肥胖和心力衰竭中的激活机制。大多数受邀发言者已同意参加，将鼓励年轻调查人员参加。将分配时间进行非正式讨论和社会互动。来自美国和其他国家的科学家、年轻的研究人员和女性在该项目中都有很好的代表。

DESCRIPTION (provided by the applicant): This is an application for partial funding of a FASEB Summer Research Conference on "Neural Mechanisms in Cardiovascular Regulation" to take place in Snowmass, Colorado on July 20-25, 2001. The conference will be the 8th in a series of FASEB Conferences held once every 2-3 years on this topic. Neural mechanisms play a major role in regulation of arterial pressure, modulation of cardiac and renal function, and occurrence of syncope, cardiac arrhythmias, and sudden death in pathological states. The conference will be of interest to both basic scientists interested in fundamental neural mechanisms, integrative physiologists, and clinicians interested in mechanisms of cardiovascular dysregulation in disease. The goal of the conference is to bring together investigators and trainees from a variety of scientific areas to discuss important aspects of neurocardiovascular control in an informal setting. The unique format and informal setting of the FASEB Summer Research Conference facilitates interactions between various disciplines and between trainees and established investigators. Specific objectives are to: 1) provide state-of-the-art overviews of important areas of neurocardiovascular regulation by recognized experts and promising young investigators; 2) identify new experimental approaches and hypotheses for future research; and 3) involve a large number of trainees and young investigators in the conference. Approximately 160 conference attendees will be selected from interested applicants. The conference will include 9 plenary sessions consisting of 4 presentations each, extended discussion sessions, and poster presentations. The plenary sessions include: 1) Mechanisms of sensory transduction in the cardiovascular system; 2) Neurotransmitters and techniques in the brainstem; 3) Exciting the RVLM: what drives the activity of RVLM vasomotor neurons? 4) Contributions by the brain in hypertension; 5) Forebrain mechanisms and neurohumoral control; 6) Central control of blood pressure and fluid homeostasis: the functional genomics era; 7) Regulation of circulation by higher brain centers; 8) Origins of cardiovascular variability, and its functional implications; and 9) Mechanisms of activation, of the sympathetic nervous system in aging, obesity and heart failure. The majority of invited speakers have already agreed to participate and participation of young investigators will be encouraged. Time will be allotted for informal discussions and social interaction. Scientists from the United States and other countries, young investigations and women are well-represented in the program.