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PH II STUDY RECOMBINANT PLATELET ACTIVATING FACTOR ACETYLHYDROLASE

PH II STUDY RECOMBINANT PLATELET ACTIVATING FACTOR ACETYLHYDROLASE
PH II 研究重组血小板激活因子乙酰水解酶
批准号：
6304642
负责人：
ADAM SLIVKA
金额：
$0.3万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6304642
关键词：
clinical research disease /disorder prevention /control endoscopy human subject human therapy evaluation iatrogenic disease immunotherapy longitudinal human study pancreatitis platelet activating factor recombinant proteins

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中文摘要
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英文摘要
The objectives of this study are: 1)to determine if the prophylactic administration of rPAF-AH decreases in incidence and severity of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis in a dose-dependent manner. 2)to evaluate the cost-efficacy of rPAH-AH when administered prophylactically to prevent post-ERCP pancreatitis. 3)to characterize the safety and pharmacokinetic behavior of rPAH-AH after intravenous administration in patients scheduled to undergo ERCP.
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PH II STUDY RECOMBINANT PLATELET ACTIVATING FACTOR ACETYLHYDROLASE