Haiti Comprehensive AIDS/TB Research Training

描述(由申请人提供)：本提案是为海地太子港的GHESKIO中心准备ICOHRTA-AIDS/TB计划。由Jean Pape领导的GHESKIO中心是海地的一个非政府研究和培训组织，与海地政府密切合作，研究艾滋病毒以及结核病和性传播感染等相关疾病。Pape博士和GHESKIO博士与康奈尔大学的Warren Johnson博士合作了20年，与Vanderbilt大学的Peter Wright博士合作了10年。这种长期的研究和培训合作最终发表了许多出版物，最近在GHESKIO启动了艾滋病毒疫苗第二阶段试验。(HVTN议定书026)这三个伙伴目前正在为五笔国立卫生研究院赠款和两笔联合国毒品和犯罪问题办事处/世界银行/世卫组织在海地的研究和培训赠款开展合作。 ICOHRTA-ALDS/TB项目在海地的研究基地将是1)通过NIH、HVTN和HPTN对艾滋病毒疫苗和阴道杀菌剂进行的艾滋病毒预防临床试验。2)成人和儿童高效抗逆转录病毒疗法(HAART)和结核病疗法的治疗临床试验3)业务和卫生科学研究，以支持将GHESKIO的服务活动扩大到海地的25个省卫生中心。这一扩展得到了海地卫生部、美国国际开发署和法国合作使团的支持。 盖斯基奥有一个分三步走的战略，为福格蒂国际中心制定一份提案 ICOHRTA-艾滋病/结核病方案。这三个步骤是：1)巩固现有的合作关系，并确定与国家、地区和国际合作伙伴的研究培训计划；2)建立GHESKIO的组织结构，以完成这一培训计划；3)制定长期的机构发展计划，以支持该计划在未来的实施。将与主要合作伙伴举行一系列4个讲习班，使GHESKIO能够循序渐进地制定ICOHRTA-ALDS/TB提案。

DESCRIPTION (provided by applicant): This proposal is for the GHESKIO Centers in Port au Prince Haiti to prepare for the ICOHRTA-AIDS/TB program. The GHESKIO Centers, directed by Jean Pape, is a Haitian non-governmental research and training organization working in close partnership with the Haitian Government on HIV and inter-related diseases such as tuberculosis and sexually transmitted infections. Dr Pape and GHESKIO have collaborated with Dr Warren Johnson of Cornell University for 20 years and Dr Peter Wright of Vanderbilt University for 10 years. This long research and training collaboration has culminated in numerous publications and the recent launch of a Phase 2 HIV vaccine trial at GHESKIO. (HVTN Protocol 026) The three partners are currently collaborating on five NIH grants and two UNOP/World Bank/WHO TOR grants for research and training in Haiti. The research base for the ICOHRTA-AlDS/TB program in Haiti will be 1) HIV prevention clinical trials of HIV vaccines and vaginal microbicides through the NIH HVTN and HPTN. 2) Therapeutic clinical trials for adults and children of highly active antiretroviral therapy (HAART) regimens and tuberculosis regimens 3) Operational and health science research in support of an expansion of GHESKIO service activities to 25 departmental health centers in Haiti. This expansion is being supported by the Haitian MOH, the United States Agency for International Development, and Mission of French Cooperation. GHESKIO has a three-step strategy to develop a proposal for The Fogarty International Center's ICOHRTA-AlDS/TB program. The three steps are 1) Consolidate existing collaborations and define the research training program with national, regional, and international partners 2) Establish the GHESKIO organizational structure to accomplish this training program and 3) Prepare a long-term institutional development plan to sustain the program in the future. A series of 4 workshops with key partners will be held that will allow GHESKIO to proceed in a step-by-step fashion towards the development of an ICOHRTA-AlDS/TB proposal.