Adherence Intervention--Late Middle-Aged /Older Adults

描述(申请人提供)：越来越多的人与 艾滋病毒/艾滋病患者年龄在50岁或以上。他们中的许多人都是中老年 有人报告难以保持严格遵守抗逆转录病毒药物 养生法。这一点很重要，因为始终坚持使用复杂的艾滋病毒 服药方案对于实现和维持健康改善至关重要。 结果。然而，到目前为止，艾滋病毒遵从性干预措施尚未具体 目标是这个年龄段。量身定做的干预措施旨在满足 迫切需要满足中老年老年人的需求。我们是 建议设计和试点一项实验性干预措施，以增加 中老年人群对抗逆转录病毒治疗的依从性 艾滋病毒携带者。干预措施的发展将由 行为改变的跨理论模型与多成分干预 激励性面试技巧与行为学相结合的策略 技能培训。拟议的调查将分四个阶段进行 在两年的研究期内。一系列规划和发展 活动将包括：(1)与中老年和老年人开展专题小组 老年人服用抗逆转录病毒药物以评估依从性问题和 干预偏好；(2)设计和测试干预的可行性和 个体和群体依从性干预的可接受性研究 50岁或以上艾滋病毒携带者的表格；(3) 干预效果的试点测试；(4)编写干预手册 材料将构成随后提出的全面调查的基础 实验干预的随机临床试验。有一个很棒的 需要有效的遵守干预措施和可行的交付方法 将其提供给服务不足的艾滋病毒感染人群。开发一种量身定做的 旨在提高抗逆转录病毒技能和动机的干预措施 50岁及以上的艾滋病毒携带者坚持治疗将有所帮助 满足这一需求。这一规划项目是下一阶段研究的内容。 提高中老年患者抗逆转录病毒治疗依从性的必要性 以及艾滋病毒携带者和老年人。

DESCRIPTION (provided by applicant): A growing number of persons living with HIV/AIDS are aged 50 or older. Many of these late middle-aged and older persons report difficulty maintaining strict adherence to antiretroviral regimens. This is important because consistent adherence to complex HIV medication regimens is critical for achieving and sustaining improved health outcomes. However, HIV adherence interventions to date have not specifically targeted this age group. Tailored interventions designed to meet the unique needs of late middle-aged and older adults are urgently needed. We are proposing to design and pilot test an experimental intervention for increasing adherence to antiretroviral treatment among late middle-aged and older persons living with HIV. Intervention development will be guided by the transtheoretical model of behavior change and multi-component intervention strategies combining motivational interviewing techniques with behavioral skills training. The proposed investigation will be conducted in four stages over the two-year study period. A sequence of planning and developmental activities will include: (1) conducting focus groups with late middle-aged and older persons taking antiretroviral medications to assess adherence issues and intervention preferences; (2) designing and testing the feasibility and acceptability of individual-level and group-level adherence intervention formats for persons living with HIV who are 50 years of age or older; (3) pilot testing of intervention efficacy; and (4) preparing intervention manual materials which will form the basis for a subsequent proposal of a full-scale randomized clinical trial of the experimental intervention. There is a great need for effective adherence interventions and feasible methods for delivering them to underserved HIV infected populations. Development of a tailored intervention designed to enhance skills and motivation for antiretroviral adherence among persons aged 50 and older living with HIV AIDS will help address this need. This planning project constitutes the next phase of study necessary to improve antiretroviral treatment adherence in late middle-aged and older persons living with HIV.