Ultrasonic Registration of Knee Anatomy to MRI Images

描述（由申请人提供）：拟定研究将研究使用术中超声（US）图像将膝关节骨表面无创配准到术前磁共振（MR）图像的可行性。CASurgica正在开发一种手术导航系统KneeNav，用于术中规划韧带附着部位的正确位置和钻孔隧道位置，然后指导外科医生执行计划。尽管在正确的插入点上达成了一致，但外科医生在隧道放置方面存在很大的差异，据报道，ACL重建手术中隧道错位的发生率在10%-40%之间。骨隧道错位是翻修手术的主要原因。拟议的研究将提高手术的准确性，与目前的视频技术或竞争的图像引导系统。研究计划是建立一个“黄金标准”的注册精度使用重建CT扫描，基于点的表面匹配算法，光学跟踪。重建的MR模型将取代CT模型，并重新评估准确性。然后将校准US探头，然后将US表面收集替换为基于点的收集，并重新评估准确度。最后，将评估US直接配准到MR而无需重建。 拟议的商业应用：不可用。

DESCRIPTION (provided by applicant): The proposed research will investigate the feasibility of using intra-operative ultrasound (US) images to noninvasively register the bone surfaces of the knee to preoperative magnetic resonance (MR) images. A surgical navigation system, KneeNav, is being developed by CASurgica for intraoperatively planning the proper location of ligament attachment sites and drill tunnel locations and then guiding the surgeon to execute the plan. Despite agreement on the correct points of insertion, great variability exists in tunnel placement among surgeons and the rate of misplaced tunnels in ACL reconstruction surgery has been reported to be between 10-40 percent. Malpositioning of the bone tunnels is the main reason for revision surgery. The proposed research would increase the accuracy of the procedure versus current videoscopic techniques or versus competitive image guidance systems. The research plan is to establish a "gold standard" for registration accuracy using reconstructed CT scans, point-based surface matching algorithms, and optical tracking. Reconstructed MR models will be substituted for CT models and the accuracy reassessed. The US probe will then be calibrated and US surface collection will then be substituted for point based collection and the accuracy reassessed. Finally, registration of US directly to MR without reconstruction will be assessed. PROPOSED COMMERCIAL APPLICATION: Not Available.