Effect of Testosterone Treatment Combined with Dietary Restriction on Body Fat Mass and Muscle Function in Obese Men: A Randomized Controlled Trial

睾酮治疗结合饮食限制对肥胖男性体脂量和肌肉功能的影响：随机对照试验

• 批准号: nhmrc : 1055305
• 负责人: Dr Mark Ng Tang Fui
• 金额: $ 9.4万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/effect-testosterone-treatment-controlled-trial/112447
• 关键词: Effect; Testosterone; Treatment; Combined; Dietary

Obesity, an increasing health and economic burden, is associated with lowered testosterone levels in men. While both dietary restriction and testosterone treatment reduce body fat, whether a combination of these two approaches achieves a more pronounced fat mass reduction is unknown. We will conduct a rigorous 12 month clinical trial of testosterone treatment in 150 obese men with a low testosterone level. All men will receive dietary intervention to induce and maintain weight loss

肥胖是一种日益加重的健康和经济负担，与男性睾丸激素水平降低有关。虽然饮食限制和睾酮治疗都能减少体脂，但这两种方法的结合是否能实现更明显的脂肪量减少尚不清楚。我们将对150名睾酮水平低的肥胖男性进行为期12个月的严格的睾酮治疗临床试验。所有男性将接受饮食干预，以诱导和维持体重减轻