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POPULATION GENOMICS AND THE VIABILITY OF THE ENDANGERED SANJE MANGABEY (CERCOCEBUS SANJEI)IN THE UDZUNGWA MOUNTAINS, TANZANIA

坦桑尼亚乌宗瓦山脉的种群基因组学和濒临灭绝的 SANJE MANGABEY (CERCOCEBUS SANJEI) 的生存能力

基本信息

批准号：
1842584
负责人：
金额：
--
依托单位：
CARDIFF UNIVERSITY
依托单位国家：
英国
项目类别：
Studentship
财政年份：
2016
资助国家：
英国
起止时间：
2016 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=studentship-1842584
关键词：
POPULATION GENOMICS VIABILITY ENDANGERED SANJE

项目摘要

This PhD project will examine the population genomic diversity and structure of the endangered Sanje mangabeyfor the first time, use the data produced to parameterise models for population viability analysis and contributeto a management plan for this endangered and highly localised primate. As an iCASE award, the student will bebased at Cardiff University, in the Organisms and Environment Division of the School of Biosciences, and at BristolZoo Gardens, Conservation Science and Research group (BZG), which the non-academic supervisor, Dr GrainneMcCabe has recently joined to head up.This will be a truly multidisciplinary project, using core science to inform and facilitate the development of anational and regional biodiversity action plan for an increasingly threatened group of flagship taxa for eastAfrica's remaining forested areas. The project involves innovative use of population genomics (genomic host DNAcapture from fecal material), including bioinformatics analysis of genome-wide single nucleotide polymorphismdata to elucidate population-level genomic diversity and differentiation between the last two populations ofSanje mangabeys in Tanzania. The application of genomics to conservation has recently received a lot ofattention (eg Shafer et al 2015, TREE 30: 78), in which the academic supervisor as co-Chair of the recentlyestablished IUCN specialist group in Conservation Genetics, has been active.The proposed studentship will therefore act as a model in which genome-wide diversity (as opposed to DNAprofiling using a handful of genetic markers) will be applied to conservation prioritisation, and the student will bebased in a laboratory internationally recognised to be leading in this area of research. In addition to the genomicsanalysis, the project will use both genetic and demographic data to carry out a population viability assessment(PVA) for the species with the aim of proposing targeted conservation actions.The student will be embedded within BZG's Tanzania program and will be not only carrying out much of the fieldwork associated with the project but will also, in collaboration with the non-academic supervisor, help developboth a species-specific and region-wide conservation management plan for forest primates in the region. This willprovide highly relevant skills for future application within a conservation context.

这个PHD项目将首次研究濒危物种Sanje manga的种群基因组多样性和结构，使用产生的数据来参数化种群生存分析的模型，并为这种濒危和高度本地化的灵长类动物的管理计划做出贡献。作为iCASE的奖项，这名学生将在卡迪夫大学、生物科学学院生物和环境部以及布里斯托尔动物园花园的保护科学和研究小组(BZG)工作，非学术导师GrainneMcCabe博士最近加入了该小组。这将是一个真正的多学科项目，利用核心科学为非洲东部剩余林区日益受到威胁的旗舰类群制定国家和区域生物多样性行动计划。该项目涉及创新使用种群基因组学(从粪便材料中捕获基因组宿主DNA)，包括对全基因组单核苷酸多态数据进行生物信息学分析，以阐明种群水平的基因组多样性和坦桑尼亚最后两个种群之间的差异。基因组学在保护中的应用最近受到了很多关注(例如Shafer等人2015年，TREE 30：78)，其中学术导师作为最近成立的IUCN保护遗传学专家组的联合主席一直很活跃。因此，拟议的学生身份将作为一个模式，将全基因组多样性(而不是使用少数几个遗传标记的DNA图谱)应用于保护优先顺序，学生将在国际公认的这一研究领域领先的实验室工作。除了基因组分析，该项目还将使用遗传和人口统计数据对该物种进行种群生存评估(PVA)，目的是提出有针对性的保护行动。该学生将被嵌入BZG的坦桑尼亚项目，不仅将执行与该项目相关的大部分实地工作，还将与非学术主管合作，帮助制定该地区森林灵长类动物特定物种和区域范围的保护管理计划。这将为未来在保护环境中的应用提供高度相关的技能。