Development of the application of bacteriophages in the removal of odour-producing bacteria from meat

噬菌体在去除肉类产臭菌中的应用进展

• 批准号: 1898602
• 金额: --
• 依托单位: University of Leicester
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-1898602
• 关键词: Development; application; bacteriophages; removal; odour

When vacuum-packed meat is first opened it is not uncommon for consumers to smell a bad odour. This smell, caused by typically harmless but odour-producing bacteria, can discourage consumers as they may presume the meat has gone off but generally washing the meat helps to remove the smell. However, if consumers are unaware of this it can lead to economic loss and negatively impact the commercial product brand. Previous studies have identified species of the Lactobacillales order, otherwise known as lactic acid bacteria (LAB), as the causative agents of the odour production. Contamination of meat by LAB may occur at any stage of the production line and these species of bacteria are microaerophiles that can grow at low temperatures making the vacuum-packed meat the ideal environment for their growth. A promising approach to the removal of these bacteria is to exploit bacteriophages (phages), which are naturally occurring viruses that are able to kill bacteria. The FDA has classed phages, as safe and commercial phage products are available on the market, such as a phage cocktail to prevent Listeria in ready meals, meat and fruit. This research aims to determine whether phages could be used during the meat processing and packaging process to prevent the growth of LAB and consequently the production of bad odours with an ultimate goal of reducing the amount of meat wasted as a result of bad odours.

当真空包装的肉第一次打开时，消费者闻到一股难闻的气味并不罕见。这种气味是由通常无害但产生气味的细菌引起的，可能会让消费者感到沮丧，因为他们可能认为肉已经变质了，但通常清洗肉有助于去除气味。然而，如果消费者没有意识到这一点，就会导致经济损失，并对商业产品品牌产生负面影响。以前的研究已经确定了乳酸杆菌目的物种，或者被称为乳酸菌（LAB），作为气味产生的病原体。肉类被LAB污染可能发生在生产线的任何阶段，这些细菌是微生物，可以在低温下生长，使真空包装的肉类成为它们生长的理想环境。清除这些细菌的一种很有希望的方法是利用噬菌体（噬菌体），这是一种能够杀死细菌的自然产生的病毒。美国食品和药物管理局将噬菌体归为一类，因为市场上有安全和商业化的噬菌体产品，比如一种用于预防即食食品、肉类和水果中的李斯特菌的噬菌体鸡尾酒。本研究旨在确定在肉类加工和包装过程中是否可以使用噬菌体来阻止乳酸菌的生长，从而产生恶臭，最终目的是减少因恶臭而浪费的肉类数量。