CORE--TRANSGENIC MOUSE

核心——转基因小鼠

• 批准号: 6444575
• 负责人: ELIZABETH H LACY
• 金额: $ 15.75万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-01-01 至 2001-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6444575
• 关键词: animal care; animal colony; antisepsis; biomedical facility; cryopreservation; disease /disorder model; gene targeting; genetically modified animals; laboratory mouse; microinjections; model design /development; transfection; veterinary medicine

The transgenic Mouse Facility generates transgenic mice for studies on gene regulation and function in embryonic and adult tissues. Transgenic mice are prepared by either DNA injection into the pronuclei of fertilized eggs or the injection of embryonic stem cells into host blastocysts.

转基因小鼠设施产生转基因小鼠用于研究 胚胎和成体组织中的基因调控和功能。转基因 通过将DNA注射到受精卵的原核中来制备小鼠， 卵子或将胚胎干细胞注射到宿主胚泡中。