Core--Animal facility

动物核心概述动物核心的目的是为项目研究者提供科学和技术支持，以设计和执行其研究。该核心的具体目标是：1.为了在动物中诱导糖尿病并使动物保持健康状态（常规监测是否符合糖尿病动物的健康标准）和血糖控制水平，2.协调项目研究者之间实验动物组织和体液的采集和分配。协助科学和执行涉及动物特殊饮食和药物治疗的方案，以及4。为计划项目的新研究者提供使用糖尿病及其并发症动物模型的培训。由我们动物研究部门负责人（V. Monnier，MD，T.克恩，博士），和60%的全职研究助理谁将承担与CWRU动物资源中心的工作人员合作的设施的日常运作）。

Summary ANIMAL CORE The objective of the Animal Core is to provide investigators of the Program Project with scientific and technical support for the design and execution of their studies. The specific aims of this core are: 1. To induce diabetes in animals and maintain the animals in a healthy state (routinely monitored for compliance with standards of health appropriate for diabetic animals) and in carefully controlled levels of glycemic control, 2. To coordinate the acquisition and distribution of tissues and body fluids from experimental animals among Program Project investigators, 3. To provide assistance with scientific and execution of protocols involving special diet and pharmacological treatments in animals, and 4. To provide training for new investigators of the Program Project in the use of animal models of diabetes and its complications. Service to the Investigators of the Program Project will be provided by a team consisting of the director of our unit for animal studies (V. Monnier, MD, T. Kern, PhD), and a 60% FTE Research Assistant who will assume the day-to-day operation of the facility in collaboration with the staff of the Animal Resources Center at CWRU).