INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARD (T32)

描述(申请者描述)：爱荷华大学肿瘤学 科研培训计划旨在支持博士后研究 在导师的环境中培训优秀的医学博士S和博士S谁希望 成为癌症研究人员并获得必要的知识和技能 进行独立的癌症研究，包括基础实验室和临床研究 研究。该项目基于30名经验丰富的教师的专业知识。 爱荷华大学癌症中心的成员。 一般的专业领域包括1)癌症免疫治疗，2)细胞 激活和肿瘤生物标记物，3)临床肿瘤学，重点是 泌尿外科肿瘤学和骨髓移植，4)分子机制 转移，5)自由基与癌症，6)癌症流行病学。这个 大多数应聘者将拥有医学博士学位，并已完成这两个学位 他们的住院医师培训和临床强化部分 分专业肿瘤学培训。少数实习生将拥有博士学位和 明确承诺致力于癌症研究事业。在此期间 支持，至少75%的参与者的时间将用于 癌症研究培训。该计划将以加州大学为基地 爱荷华州癌症中心。为期三年的课程将分为初级阶段 一年(核心年)和两年直接用于研究培训 (研究年数)。在核心年的前六个月，所有受训人员 将参与临床研究和基础研究轮换以获得 熟悉最先进的基础肿瘤学的各个方面 S研究。此外，他们还将参加癌症生物学的课程， 流行病学/生物统计学、信息学和医学伦理学。他们还将 在以下导师的指导下开始一段密集的癌症研究培训 一位经验丰富的癌症调查员。指导研究将在以下期间继续进行 研究年限。受训人员的进度将由一个 个人指导委员会和计划咨询委员会和计划 导演。计划完成后，预计学员将拥有 对癌症研究的各个方面有透彻的了解，并 能够在学术环境中作为独立的癌症研究人员发挥作用。

DESCRIPTION (Applicant's Description): The University of Iowa Oncology Research Training Program is designed to support postdoctoral research training in a mentored environment for outstanding M.D.'s and Ph.D.'s who wish to become cancer researchers and acquire the knowledge and skills necessary to perform independent cancer research including basic laboratory and clinical research. The program is based on the expertise of 30 experienced faculty members who are members of the Cancer Center at the University of Iowa. General areas of expertise include 1) Cancer immunotherapy, 2) Cellular activation and tumor biomarkers, 3) Clinical oncology with an emphasis on urologic oncology and bone marrow transplantation, 4) Molecular mechanisms of metastasis, 5) Free radicals and cancer, and 6) Cancer epidemiology. The majority of candidates will have the M.D. degree, and have completed both their residency training and the clinically intensive portion of their subspecialty oncology training. A minority of trainees will have a Ph.D. and a stated commitment to pursuing a career in cancer research. During the period of support, at least 75 percent of participants' time will be devoted to cancer research training. The program will be based within The University of Iowa Cancer Center. The three-year curriculum will be divided into the initial year (core year) and two years dedicated directly to research training (research years). During the first six months of the core year, all trainees will participate in clinical research and basic research rotations to gain a familiarity with various aspects of state-of-the-art basic oncologic r e s earch. In addition, they will attend classes in cancer biology, epidemiology/biostatistics, informatics, and medical ethics. They will also begin an intensive period of cancer research training under the mentorship of an experienced cancer investigator. Mentored research will be continued during the research years. Progress of trainees will be monitored continuously by a personal mentoring committee and by the program advisory committee and Program Director. On completion of the program, it is expected that trainees will have a thorough understanding of the various aspects of cancer research, and be able to function as independent cancer researchers in an academic setting.