Ending Tuberculosis. A cluster RCT of community-wide universal testing and treatment for latent TB infection in high prevalence settings

终结结核病。

• 批准号: nhmrc : GNT1165636
• 金额: $ 645.81万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/ending-tuberculosis-cluster-prevalence-settings/1379415
• 关键词: Ending; Tuberculosis.; cluster; RCT; community

This year 10 million people will develop tuberculosis (TB) and two million people will die from the disease. WHO have set ambitious targets to END TB by the 2035 but these will not be achieved by current approaches. We propose to test a new strategy, “universal test and treat” for TB infection, in a randomised controlled trial to be conducted in a remote rural province of Vietnam. If successful and scaled up, this new strategy could lead to the elimination of TB as a public health problem.

今年将有1 000万人患上结核病，200万人将死于这种疾病。世卫组织制定了到2035年终结结核病的宏伟目标，但这些目标将无法通过目前的方法实现。我们建议在越南一个偏远的农村省份进行一项随机对照试验，以测试一种新的策略，即结核病感染的“通用检测和治疗”。如果成功并扩大规模，这一新战略可能导致消除结核病这一公共卫生问题。