CORE--FUNCTIONAL GENOMICS AND MOLECULAR BIOLOGY

核心--功能基因组学和分子生物学

• 批准号: 6588131
• 负责人: MICHAEL STEVEN DENISON
• 金额: $ 7.35万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-22 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6588131
• 关键词: agriculture; biomedical facility; biotechnology; environmental toxicology; functional /structural genomics; gene interaction; high throughput technology; microarray technology; molecular biology; nucleic acid chemical synthesis; nucleic acid sequence; training

Description (provided by applicant): This facility core has been operating under the name of Molecular Biology Facility Service Core since the beginning of the Center in 1993. The name of this Core has been changed at this time of competitive renewal in accordance with the recommendation made by the New Directions Committee. This change is intended to expand the duty of the Core from the classic nucleic acid technology lab to a group of modern labs to include functional genomics. The term "functional" is interpreted to keep expanding the frontier that is created by high-throughput genomic research on gene expression to move into the actual functions of proteins produced and their interactions. Reflecting the complexity of these ever-expanding cutting-edge sciences/technologies. The main objective of this service and facility core is to promote the use of modern techniques and approaches in functional genomics and molecular biology among Center investigators, their collaborators, affiliate scientists, and pilot project recipients. The Core functions to provide access, training, and assistance to students, postdoctoral fellows, and staff members with regards to specific molecular techniques and instrumentation, to offer expert advice in experimental design and approaches using these technologies, to assist in data analysis and interpretation and method troubleshooting, to suggest appropriate reference materials and information relative to specific techniques and methodological approaches, to act as a general resource to assist in the integration of molecular biology into existing programs and projects, and to facilitate the education of Center researchers in molecular biological approaches and techniques. Accordingly, the teaching and training of graduate students and staff is an integral part of the operation.

描述（申请人提供）：此设施核心一直在运行 从一开始就以分子生物学设施服务核心的名义 该中心于1993年。此核心的名称已更改 根据新的建议，竞争性更新 方向委员会。这种变化旨在扩大核心的职责 从经典的核酸技术实验室到一组现代实验室到 包括功能基因组学。 “功能”一词被解释为保留 扩展高通量基因组研究创建的边界 基因表达进入产生的蛋白质的实际功能， 他们的互动。反映这些不断扩展的复杂性 尖端科学/技术。 这项服务和设施核心的主要目的是促进使用 功能基因组学和分子生物学的现代技术和方法 在中心调查员，他们的合作者，会员科学家和 飞行员项目收件人。提供访问，培训和 为学生，博士后研究员和有问候的工作人员提供帮助 为特定的分子技术和仪器提供专家建议 在实验设计和使用这些技术的方法中，以协助 数据分析，解释以及方法故障排除，建议 相对于特定的适当参考材料和信息 技术和方法论方法，充当一般资源 协助将分子生物学整合到现有程序中，并 项目，并促进中心研究人员的分子教育 生物学方法和技术。因此，教学和培训 研究生和教职员工是行动不可或缺的一部分。