Clinical Search Retrieval from 4 Electronic Databases

描述(由申请人提供)： 这项继续提案中的项目是一系列调查的一部分，这些调查寻求开发和利用搜索策略(“对冲”)的方法，这些策略将改善从大型、通用、生物医学研究书目数据库(包括MEDLINE、EMBASE、心理LIT和CINAHL)中检索临床相关和科学合理的研究报告。长期目标是利用这些电子数据库中与临床最相关的内容，以便最终能够测试它们对临床实践的影响。在我们之前使用MEDLINE的研究中，我们记录了超过60,000个“方法学模糊限制语”的检索性能，即搜索策略，旨在检测符合有效性和临床实践适用性的关键科学标准的应用型临床研究研究。目前正在进行一个项目，以在最近的MEDLINE文件中以及在EMBASE、JuncLIT和CINAHL中扩展这项研究。在这项研究中创建的数据库可以用来回答新的问题，具体地说：a)在MEDLINE、EMBASE、JuncLIT和CINAHL 2000年的文件中，定义了对关于人类疾病的经济方面的临床问题、临床预测问题以及导致文献回顾的临床问题最重要的研究的方法学术语的操作特征是什么？B)这些单个年龄相关术语的电子数据库中检索特定年龄特定医学领域的研究的操作特点是什么，当与最高产出的方法学搜索策略结合时，最高产出策略的表现如何？C)对于不同的临床内容领域，文章在多大程度上聚集在期刊子集中，当在期刊子集中运行搜索时，搜索的精确度会受到什么影响？D)我们手工检索的数据库中收录的期刊的产量与期刊影响因子之间的相关性是什么？为了创建和评估搜索策略，索引项和文本词被视为“诊断测试”，对文献的手动搜索被视为“黄金标准”。手工检索的文献被定义为具有相关内容并符合临床实践的基本方法学标准。这些战略的运作特点在4个电子数据库中确定。

DESCRIPTION (provided by applicant): The projects in this continuation proposal are part of a series of investigations seeking ways to develop and harness search strategies ("hedges") that will improve retrieval of clinically relevant and scientifically sound study reports from large, general purpose, biomedical research bibliographic databases including MEDLINE, EMBASE, PsycLIT, and CINAHL. The long-term objective is to harness the most clinically relevant content of these electronic databases so that their effects on clinical practice can be eventually tested. In our previous research Using MEDLINE, we documented the retrieval performance of over 60,000 "methodologic hedges", that is, search strategies designed to detect applied clinical research studies that meet key scientific standards for validity and applicability to clinical practice. A project is currently underway to extend this research in recent MEDLINE files and in EMBASE, PsycLIT, and CINAHL. The database created in this research can be used to answer new questions, specifically: A) What are the operating characteristics, in year 2000 files of MEDLINE, EMBASE, PsycLIT, and CINAHL, of methodologic terms that define studies of the most importance to clinical questions about the economic aspects of human disorders, to questions about clinical prediction, and to clinical questions that lead to a review of the literature? B) What are the operating characteristics in these electronic databases of individual age-related terms for retrieving studies of a particular age-specific area of medicine, and how do the top yielding strategies perform when combined with top yielding methodologic search strategies? C) For diverse clinical content areas, to what extent are articles clustered in journal subsets, and how is the precision of searching affected when running searches in journal subsets? D) What is the correlation between journal impact factors and yield from the journals included in our hand searched database? To create and evaluate the search strategies, index terms and text words are treated as 'diagnostic tests' and a hand search of the literature is treated as the 'gold standard'. Articles are defined as having relevant content and meeting basic methodologic criteria for clinical practice by the hand search. The operating characteristics of these strategies are determined in the 4 electronic databases.