Enhanced Control of Hypertension and Thrombolysis in Stroke Study (STAY ENCHANTED)

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'Clot busting' treatment is the only approved medical treatment for the commonest type of stroke, ischaemic stroke. However, uptake of treatment remains poor, mainly due to the known major risk of bleeding in the brain. STAY ENCHANTED is an international clinical trial to investigate whether 'clot-busting' can be made safer using a lower dose and/or immediate blood pressure lowering. A safer more effective regime could have a major global health impact.