Presentation: Precision PC Stimulation for Neuroscience

描述（由申请人提供）：精确和灵活的刺激传递， 实验控制（SDEC）是研究知觉和 高级认知功能我们开发了Presentation，一个Windows SDEC 一个程序，提供复杂的多模态刺激和监测反应， 精确的时间。我们现在请求第二阶段的支持，以增加创新的新功能 包括（1）使用呈现的自适应刺激递送 控制语言（PCL）。PCL允许刺激在真实的时间内基于 性能或生理反应，允许自动调整任务 困难，计算机控制的神经元感受野的测定， 逐帧显示控制对于基于计算机的 神经康复((2)图形和音频刺激生成使用 高级Direct 3D和DirectSound命令。这些将允许听觉和 在3D空间中定义和操纵视觉刺激。立体视觉和 触觉刺激功能也将通过DirectX 8.0实用程序添加。 (3)刺激生成模块接口（SGMI），允许用户程序 在呈现实验期间呈现定制刺激。(4)实时流 精确的逐帧控制视频，使实验成为可能， 数字化和合成的视频序列;（5）易于使用的实验工具 创建和分析，以促进开发和分析 实验方案。这些补充将使介绍一个无与伦比的 SDEC平台用于第三阶段产品发布。 拟定商业应用： 建议的项目将直接导致一个商业的基于PC的刺激交付/实验控制软件包。

DESCRIPTION (provided by applicant): Precise and flexible stimulus delivery and experimental control (SDEC) are essential for studies of perception and higher-cognitive functions. We have developed Presentation, a Windows SDEC program that delivers complex multimodal stimuli and monitors responses with precise timing. We now request Phase II support to add innovative new features to Presentation including (1) Adaptive stimulus delivery using the Presentation Control Language (PCL). PCL permits stimuli to be altered in real time based on performance or physiological responses, allowing automated adjustments in task difficulty, computer-controlled determination of neuronal receptive fields, and frame-by-frame display control important for computer-based neuro-rehabilitation. ((2) Graphic and audio stimulus generation using high-level Direct3D and DirectSound commands. These will permit auditory and visual stimuli to be defined and manipulated in 3D space. Stereovision and tactile stimulation capabilities will also be added sing DirectX 8.0 utilities. (3) A stimulus generation module interface (SGMI), permitting user programs to present custom stimuli during Presentation experiments. (4) Real-time streaming video with precise frame-by-frame control, making possible experiments with digitized and synthesized video sequences; (5) Easy-to-use tools for experiment creation and analysis to facilitate the development and analysis of experimental protocols. These additions will make Presentation an unexcelled SDEC platform for Phase III product launch. PROPOSED COMMERCIAL APPLICATION: Te proposed project will lead directly to a commercial PC-based stimulus delivery / experimental control software package.