A Multifunctional Photoredox-Organocatalyst System for Small Molecule Activation

用于小分子活化的多功能光氧化还原有机催化剂系统

• 批准号: 2089334
• 金额: --
• 依托单位: University of St Andrews
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2089334
• 关键词: Multifunctional; Photoredox; Organocatalyst; System; Small

Homogeneous photoredox catalysis offers an intriguing alternative to traditional thermally-promoted reactions.1 These photochemically driven processes use an abundant, cheap energy source (the sun or ambient light) under mild reactions conditions and employ well-defined catalysts that act to efficiently harness photochemical energy. Typical photoredox catalysts (PRC) consist of RuII or IrIII complexes, though other photophysically active complexes based on AuI, ReI, CuI and PtII have all been explored. Few studies have systematically probed the optoelectronic properties of the catalysts or designed bespoke PRCs in order to tune their reactivity.This proposal targets the synthesis, design and application of organic TADF compounds as PRCs with the following goals: 1) design and synthesis of very high triplet energy PRCs; 2) utilization of these PRCs for reduction of aryl chlorides and alkyl halides that is currently generally not applicable; 3) further increase reactivity through dual substrate activation with an organocatalyst; 4) design an all-in-one system that contains both the PRC and organocatalyst functionality.

与传统的热促进反应相比，均相光氧化还原催化提供了一种有趣的替代方法。1这些光化学驱动的过程在温和的反应条件下使用丰富、廉价的能源(太阳或环境光)，并采用定义明确的催化剂，有效地利用光化学能。典型的光氧化还原催化剂(PRC)由RuII或IrIII络合物组成，尽管基于AUI、REI、CuI和PtII的其他光物理活性络合物都已被探索过。很少有研究系统地探索催化剂的光电性质，或设计定制的催化剂以调节其反应活性。本建议的目标是合成、设计和应用有机TADF化合物作为催化剂，目标如下：1)设计和合成非常高的三重态能量的催化剂；2)利用这些催化剂还原目前通常不适用的芳基氯化物和卤代烃；3)通过有机催化剂的双重底物活化进一步提高反应活性；4)设计一个同时具有PRC和有机催化剂功能的一体化系统。