FASEB CONFERENCE: Nucleic Acids

拟议的会议题为“核酸酶：结构、机制和新应用”，将重点讨论作用于DNA和RNA的酶的结构、机制、生物学作用和医学相关性。会议旨在吸引具有结构生物学、生物化学和细胞生物学专业知识的广泛的跨学科科学家小组。会议提供了一个独特的论坛，讨论有关作用于核酸的新酶的爆炸性信息，DNA和RNA酶学在生物技术中的核心作用，以及涉及核酸酶的人类代谢紊乱和疾病的日益增多的清单。通过将结构生物学家、生化学家、细胞生物学家和临床医生聚集在一起讨论共同的兴趣，将培养新的见解和跨学科的合作。科学计划将由以下主题领域的杰出受邀演讲者进行九次口头报告：(1)DNA修复酶；(2) DNA和RNA聚合酶；(3)重组和基因重排(4)DNA和RNA修饰酶；(5)解旋酶和核酸依赖性NTPases；(6) RNA及RNA催化剂(7)裂解与降解酶(8)新技术与生物信息学(9)核酸酶学相关疾病。组织者已经招募了主要的调查人员作为这些会议的讨论领导。该计划还将包括每日海报会议。所有与会者都将被鼓励展示他们研究的海报。为了鼓励青年科学家的职业发展，将从研究生和博士后参会者中选出6名优秀的海报进行简短的口头报告。FASEB 2002会议旨在强调核酸酶学中的几个新兴主题，包括新酶对DNA和RNA的动态重排和修饰，参与DNA代谢的酶与RNA世界的酶之间的相似之处，以及核酸酶对生物技术和医学的迅速影响。会议的亲密形式旨在促进从事RNA和DNA酶不同方面工作的研究人员之间的信息和思想的自由交流，从而加快这两个领域的研究。

The proposed meeting entitled "NUCLEIC ACID ENZYMES: STRUCTURES, MECHANISMS AND NOVEL APPLICATIONS" will focus on the structures, mechanisms, biological roles, and medical relevance of enzymes that act on DNA and RNA. The meeting aims to attract a broad cross-disciplinary group of scientists with expertise in structural biology, biochemistry, and cell biology. The meeting provides a unique forum for discussing the explosion of information on new enzymes that act on nucleic acids, the central role of DNA and RNA enzymology in biotechnology, and the growing list of human metabolic disorders and disease in which nucleic acid enzymes are implicated. By bringing together structural biologists, biochemists, cell biologists and clinicians to discuss common interests, new insights and interdisciplinary collaboration will be fostered. The Scientific Program will consist of nine sessions of oral presentations by distinguished invited speakers in the following subject areas: (1) DNA repair enzymes; (2) DNA and RNA polymerases; (3) Recombination and genetic rearrangements (4) DNA and RNA modification enzymes; (5) Helicases and nucleic acid-dependent NTPases; (6) RNA and RNA catalysts (7) Cleavage and degradative enzymes (8) New techniques and bioinformatics (9) Diseases related to nucleic acids enzymology. The organizers have recruited leading investigators to serve as Discussion leaders for these sessions. The Program will also include daily poster sessions. All attendees will be encouraged to present posters on their research. To encourage career development of junior scientists, six outstanding posters from the ranks of graduate students and post-doc attendees will be selected for short oral presentations. The FASEB 2002 meeting aims to highlight several emerging themes in nucleic acids enzymology including the dynamic rearrangement and modification of DNA and RNA by novel enzymes, the parallels between enzymes involved in DNA metabolism and those of the RNA world, and the burgeoning impact that nucleic acid enzymes are having on biotechnology and medicine. The intimate format of the conference is designed to promote free exchange of information and ideas among researchers who work on diverse aspects of RNA and DNA enzymes- thereby expediting research in both fields.