Xth Int'l Symposium on Human Chlamydial Infection

请求为第十届人类衣原体感染国际研讨会提供资金支持。沙眼衣原体感染是性传播疾病的最常见原因，往往会导致妇女和新生儿的严重病理。在向疾控中心报告的所有应报告疾病中，沙眼衣原体是美国报告的最常见的感染。它还可能增加感染艾滋病毒的风险。这些微生物也是沙眼的原因，沙眼是世界上可预防的失明的主要原因。肺炎衣原体被认为是一种非常常见的呼吸道病原体，最近肺炎衣原体与慢性呼吸道疾病和冠状动脉疾病的关联显著增加了了解这些感染的必要性。随着诊断分子技术的进步，扩大的衣原体疾病临床谱系的特征得到了便利。此外，在阐明衣原体生物与其专性哺乳动物细胞之间复杂的相互作用以及免疫和发病的分子机制方面取得了令人兴奋的进展。此外，从最近沙眼衣原体和肺炎衣原体基因组测序中推断出的信息正在迅速为基础衣原体生物学提供新的见解。这次会议是该领域研究人员交流最高质量的研究信息并在不同国家之间比较结果的最重要的聚会。鉴于最近衣原体研究的爆炸性增长，将于2002年6月举行的第十届人类衣原体感染国际研讨会是及时的，因为这一会议传统上每四年举行一次。因此，这是有利的，可以预期它将为制定新千年衣原体研究议程提供独特的动力。

Financial support is requested for the Xth International Symposium on Human Chlamydial Infection. Chlamydia trachomatis infections are the most common cause of sexually transmitted diseases often resulting in severe pathology in women and newborns. Of all notifiable diseases reported to the CDC, C. trachomatis is the most prevalent reported infection in the United States. It may also increase the risk of HIV infection. These organisms are also the cause of trachoma, the leading cause of preventable blindness in the world. C. pneumoniae is recognized as a very common respiratory pathogen and the recent association of C. pneumoniae with chronic respiratory diseases and coronary artery diseases significantly increases the need for understanding these infections. Characterization of the expanded clinical spectrum of chlamydial diseases has been facilitated by advances in molecular techniques for diagnosis. This has been complemented by exciting advances in elucidating the sophisticated interplay between chlamydial organisms and their obligate mammalian cells and the molecular mechanisms of immunity and pathogenesis. Additionally, the information inferred from the recent sequencing of the C. trachomatis and the C. pneumoniae genomes is rapidly providing new insights into fundamental chlamydial biology. This meeting represents the most important gathering for researchers in the field to exchange the highest quality research information and comparison of results among different countries. Given the recent explosion of research on chlamydiae, the Xth International Symposium on Human Chlamydial Infection to be held in June 2002 is timely as this meeting is traditionally held only every four years. It is thus propitious and can be expected to uniquely provide the impetus for setting the research agenda on the chlamydiae for the new millennium.