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ADOPTIVE TRANSFER OF IMMUNITY IN BONE MARROW TRANSPLANTATION

ADOPTIVE TRANSFER OF IMMUNITY IN BONE MARROW TRANSPLANTATION
骨髓移植中的过继免疫转移
批准号:
6565715
负责人:
Edmund K Waller
金额:
$29.31万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-12-01 至 2002-11-30

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中文摘要
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英文摘要
No study to date has addressed the questions of when donor immunization should occur in order to have an optimal number of primed B and T cells in the bone marrow or the stem cell harvest. This study is designed to: determine the optimal time interval to vaccinate autologous and allogeneic BM donors in order to maximize the frequency of antigen specific B-cells and T-cells in the bone marrow graft, demonstrate transfer of adoptive immunity to BMT recipients who receive bone marrow from recently vaccinated allogeneic or autologous donors, and study antigen specific B-cell and T-cell responses in vaccine recipients.
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Using donor dendritic cells to optimize GvHD and GvL in allogeneic stem cell transplantation
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  • 项目类别:
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  • 项目类别:
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Using donor dendritic cells to optimize GvHD and GvL in allogeneic stem cell transplantation
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  • 依托单位:
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