Antidepressant and antipsychotic drug use in people with diabetes

糖尿病患者抗抑郁和抗精神病药物的使用

• 批准号: 2107305
• 金额: --
• 依托单位: University of Edinburgh
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2107305
• 关键词: Antidepressant; antipsychotic; drug; use; people

In brief, the goals of this project are to identify the frequency of antidepressant and antipsychotic drug use among people with diabetes, and to investigate whether this is associated with glycemic control, blood pressure and body mass index, as well as vascular disease and diabetes specific complications. I will also examine the impact of antidepressant and antipsychotic polypharmacy.More specifically, I will investigate whether these associations differ by drug class or combination. This will help to inform subsequent projects aimed at identifying patients who might be at greatest risk of adverse effects from certain drugs, thus informing tailored drug prescription practices and ultimately providing personalised patient treatment. Datasets utilised to fulfil these goals will include the Scottish Care Information-Diabetes dataset and the South London and Maudsley NHS Foundation Trust case register.

简而言之，该项目的目标是确定糖尿病患者使用抗抑郁药和抗精神病药的频率，并调查这是否与血糖控制，血压和体重指数以及血管疾病和糖尿病特定并发症相关。我还将研究抗抑郁药和抗精神病药合用的影响，更具体地说，我将研究这些关联是否因药物类别或组合而异。这将有助于为后续项目提供信息，这些项目旨在识别可能面临某些药物不良反应风险最大的患者，从而为定制药物处方实践提供信息，并最终提供个性化的患者治疗。用于实现这些目标的数据集将包括苏格兰护理信息糖尿病数据集和南伦敦和莫兹利NHS基金会信托病例登记册。