CORE--STABLE LEAD ISOTOPE AND TRACE ELEMENT ANALYSIS

核心--稳定铅同位素和微量元素分析

• 批准号: 6578816
• 负责人: Chillrud
• 金额: $ 8.37万
• 依托单位: MOUNT SINAI SCHOOL OF MEDICINE OF CUNY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6578816
• 关键词: analytical chemistry; biomedical facility; environmental contamination; environmental toxicology; hazardous substances; lead; stable isotope; trace elements

DESCRIPTION (Taken from application) This analytical core will be housed at Lamont-Doherty Earth Observatory (LDEO) and will provide sample preparation and analyses to multiple projects of this Superfund application. This core will primarily support Project 8 (Persistent organochlorines in the Hudson River Watershed) and Project 2 (Sources and pathways of heavy metal exposure in the Hudson River Watershed and New York City). In addition, exploratory Pb isotope analyses will be made on pre-ashed blood samples from Project 3 in year 3. If these exploratory analyses prove useful, then supplemental funding will be sought at that time to expand the number of Pb isotope analyses being run for Project 3. Sample preparation will include the following matrixes: soil, sediment and particulate matter filters, as well as sample preparation on a limited number of pre-ashed blood samples. Work to be performed for Projects 8 and 2 include sample preparation and radionuclide measurements via gamma spectroscopy and stable Pb isotope measurements. Additional analyses to be performed for Project 2 include Hg concentration and multi-element analyses by flame AA and ICP-MS. Work to be performed for Project 3 in Year 3 includes sample preparation and Pb isotope analysis of pre-ashed blood samples.

描述(取自应用程序) 这个分析核心将被安置在拉蒙特-多尔蒂地球天文台(LDEO) 并将为该项目的多个项目提供样品准备和分析 超级基金申请。该核心将主要支持项目8(持久 哈德逊河流域的有机氯)和项目2(来源和 哈德逊河流域和纽约的重金属暴露途径 城市)。此外，还将对预灰进行探索性的铅同位素分析。 第三年项目3的血液样本。如果这些探索性分析证明 有用，那么届时将寻求补充资金，以扩大 为项目3进行的铅同位素分析次数：样品制备 将包括以下基质：土壤、沉积物和颗粒物 过滤器，以及对有限数量的预灰化血液进行样品制备 样本。项目8和项目2将进行的工作包括样品制备 通过伽马能谱和稳定的铅同位素进行放射性核素测量 测量。将对项目2进行的其他分析包括汞 火焰原子吸收光谱分析和电感耦合等离子体质谱多元素分析未来的工作 在第三年为项目3执行的工作包括样品制备和铅同位素 预灰化血样的分析。