Living with Cancer: Evaluation and refinement of a model

产品说明：（申请人提供）尽管有大量文献研究了癌症诊断和治疗的应对和调整，但很少有研究关注早期治疗后阶段（末次治疗剂量至治疗后12个月）、年轻人（小于或等于50岁）、性别差异或家庭观点。 这项研究将研究患有结直肠癌或淋巴瘤的年轻男性和女性[21 - 50岁]及其家人在治疗后的前12个月内如何应对和适应他们的疾病。 将解决以下具体目标：（1）开发一个理论模型，描述完成淋巴瘤或结直肠癌治疗的年轻（21 - 50岁）成人"治疗后与癌症共存"的过程;（2）利用患者的定性数据，确定不同亚组在应对和调整方面的特征主题。 定量数据将被整合到分析中，以进一步阐明应对和调整模式的这些变化;（3）确定定性主题，这些主题表征了淋巴瘤和结直肠癌治疗结束后前12个月内年轻男性和女性如何应对和调整的性别差异;（4）探讨患者与家属描述的一致性与不一致性及其对心理健康的影响。（5）将本研究建立的理论模型与现有的“慢性病生存模型”进行比较。 将在5个时间点对患者和家庭成员进行单独访谈并填写问卷包：治疗最后一天、治疗后2周和4周以及治疗后3个月和12个月。 逐字记录本将采用内容分析和不断比较的方法进行分析。 在家庭背景下确定与年龄有关的和针对性别的主题，对于制定干预战略至关重要，这些战略将促进这些年轻成年癌症幸存者及其家人恢复生产性生活并提高生活质量。

DESCRIPTION: (provided by applicant) Despite a large body of literature examining coping and adjustment to cancer diagnosis and treatment, very few studies have focused on the early post-treatment phase (last treatment dose through 12 months post-treatment), younger adults ( less than or equal too age 50), gender differences, or family perspectives. This study will examine how younger men and women [ages 21-50] with colorectal cancer or lymphoma and their families, cope and adjust to their disease during the first 12 months of post-treatment. The following specific aims will be addressed: (1) Develop a theoretical model describing the process of "living with cancer after treatment" in younger (21-50 years) adults completing treatment for lymphoma or colorectal cancer; (2) Utilizing qualitative data from patients, identify themes that characterize different subgroups in terms of coping and adjustment. Quantitative data will be integrated into the analyses to further illuminate these variations in patterns of coping and adjustment; (3) Identify qualitative themes that characterize gender differences in how younger men and women cope and adjust during the first 12 month following the end of treatment for lymphoma and colorectal cancer; (4) Explore the consonance/dissonance between the descriptions offered by the patient and family member within a dyad and its impact on the psychological well-being and overall health of the individual with lymphoma or colorectal cancer; (5) Compare and contrast the theoretical model developed in this study with the existing "Living with Chronic Illness Model". Patients and family members will be interviewed individually and complete a questionnaire packet at 5 time points: last day of treatment, 2 weeks and 4 weeks post-treatment, and 3 and 12 months post-treatment. Verbatim transcripts will be analyzed using content analysis and constant comparison. Identification of age-related and gender-specific themes within the context of the family are vital to the development of intervention strategies that will enhance the return to a productive existence and improve quality of life for these younger adult cancer survivors and their families.