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CELLULAR AND MOLECULAR STUDIES OF ETHANOL AND MEMORY

CELLULAR AND MOLECULAR STUDIES OF ETHANOL AND MEMORY
乙醇和记忆的细胞和分子研究
批准号:
6488796
负责人:
MICHAEL D BROWNING
金额:
$15.58万
依托单位国家:
美国
项目类别:
财政年份:
1993
资助国家:
美国
项目状态:
已结题
起止时间:
1993-09-30 至 2002-12-31

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中文摘要
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英文摘要
This is a second resubmission of a competing renewal application, following three years of initial support. The applicant has determined that hippocampal LTP is ethanol sensitive. NMDA receptors seem to play a clear role in this sensitivity. However, inhibition of LTP by 100 mM ethanol exceeds that produced by inhibition of NMDA receptors by other pharmacological agents, leading to the hypothesis that an additional component of the inhibition may result from a ethanol's effects on GABAA receptors. This proposal further explores the actions of ethanol on NMDA receptor function, as well as probing the contribution and nature of GABAA receptors.
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Molecular Mechanisms of Ethanol Sensitivity in ILS and ISS Mice
  • 批准号:
    7101956
  • 项目类别:
  • 资助金额:
    $33.23万
  • 财政年份:
    2005
  • 负责人:
    MICHAEL D BROWNING
  • 依托单位:
Molecular Mechanisms of Ethanol Sensitivity in ILS and ISS Mice
  • 批准号:
    7454194
  • 项目类别:
  • 资助金额:
    $32.21万
  • 财政年份:
    2005
  • 负责人:
    MICHAEL D BROWNING
  • 依托单位:
Molecular Mechanisms of Ethanol Sensitivity in ILS and ISS Mice
  • 批准号:
    7252114
  • 项目类别:
  • 资助金额:
    $32.24万
  • 财政年份:
    2005
  • 负责人:
    MICHAEL D BROWNING
  • 依托单位:
Molecular Mechanisms of Ethanol Sensitivity in ILS and ISS Mice
  • 批准号:
    6967079
  • 项目类别:
  • 资助金额:
    $34.05万
  • 财政年份:
    2005
  • 负责人:
    MICHAEL D BROWNING
  • 依托单位:
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