Development of a Bioinformatics Infrastructure

描述(由申请人提供)： 这项建议的主要目标是通过建立有效管理MSM知识环境所需的生物计算基础设施来建设研究能力和提高研究生产率。拟议的RCMI方案将作为一项发展规划赠款，分三个阶段和九个目标/目的进行。第一阶段有两个目标：1)为国际电联建立一个组织框架，使其成为该机构内的“英才中心”；2)启动以信息学研究能力建设为重点的战略规划和实施进程。第二阶段最初将侧重于招聘在生物医学信息学和信息技术方面具有特殊专长的教员和工作人员。这些人将提供成功实施在第一阶段建立的战略计划所需的领导和技术支持。第二阶段的另一个主要内容将涉及三个“发展项目”，旨在将生物医学信息学整合到基础、临床和基于人群的研究项目中。第三阶段包括将这一“示范模式”扩展到其他RCMI机构的方法，作为发展RCMI生物医学研究信息学网络的长期战略的一部分。

DESCRIPTION (provided by applicant): The major objective of this proposal is to build research capacity and enhance research productivity by establishing the biocomputing infrastructure necessary for effective stewardship of MSM's knowledge environment. The proposed RCMI Program will be structured as a developmental planning grant progressing through three phases and nine objectives/Aims. Phase I has a two-fold objective: 1) to establish an organizational framework for the BIU as a "center-of-excellence" within the institution and 2) to initiate a process of strategic planning and implementation focused on research-capacity building in informatics. Phase II will initially focus on the recruitment of faculty and staff with particular expertise in biomedical informatics and information technology. These individuals will provide the leadership and technical support needed to successfully implement the strategic plan established during Phase I. The other major element of Phase II will involve three "developmental projects" that are designed to integrate biomedical informatics into basic, clinical and population-based research programs. Phase III includes an approach for expanding this "demonstration model" to other RCMI institutions as part of a long-term strategy to develop a RCMI Biomedical Research Informatics Network.