HIVBaseR 1.0, The Genetic Data Solution

HIVBaseR 1.0，遗传数据解决方案

• 批准号: 6694726
• 负责人: Susanna L Lamers
• 金额: $ 10万
• 依托单位: GENE JOHNSON, INC.
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2004-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6694726
• 关键词: computer data analysis; computer program /software; computer system design /evaluation; data management; human immunodeficiency virus; molecular biology information system; nucleic acid sequence; virus genetics

DESCRIPTION (provided by applicant): This phase I project will support the development of software -- designated HIVbase (r) -- that will modernize the way HIV researchers manage and analyze genetic data. Today's HIV investigators possess massive amounts of research information in user-hostile formats, error-filled spreadsheets, outdated databases, directories containing thousands of individual files, and even paper records. They need to extract value from this disorganized information. We are solving their problem by developing unique applications for integrating HIV data from multiple sources into an automated high-dimensional warehouse. We are developing patent-worthy protein identification tools that will eliminate repetitious HIV sequence editing and automatically create a multifunctional, relational data system. We will provide a platform for the scientist to direct user-specific questions toward immense files of genetic data, searches that can instantly retrieve site-specific genetic attributes on thousands of sequences. The HIV research market is enormous, growing in multiple directions, and urgently in need of our proposed software. HlVbase is unique in its ability to help researchers cope with both their current backlog of genetic data and extensive new genetic data pertinent to their efforts. The informational power provided by HlVbase software has never before been available to genetic researchers. Our newly founded company, GENE JOHNSON INC., has quickly established academic and commercial collaborators who have provided ideas, data, and encouragement concerning the economic feasibility of the product.

描述（由申请人提供）： 该项目第一阶段将支持开发名为HIVbase（r）的软件，该软件将使艾滋病毒研究人员管理和分析遗传数据的方式现代化。今天的艾滋病研究人员拥有大量的研究信息，这些信息的格式对用户不利，充满错误的电子表格，过时的数据库，包含数千个单独文件的目录，甚至是纸质记录。他们需要从这些杂乱无章的信息中提取价值。我们正在通过开发独特的应用程序来解决他们的问题，将来自多个来源的HIV数据整合到自动化的高维数据仓库中。我们正在开发具有专利价值的蛋白质识别工具，该工具将消除重复的HIV序列编辑，并自动创建多功能的相关数据系统。我们将为科学家提供一个平台，将用户特定的问题导向巨大的遗传数据文件，搜索可以立即检索数千个序列的特定位点遗传属性。HIV研究市场是巨大的，在多个方向上增长，迫切需要我们提出的软件。HIVbase的独特之处在于它能够帮助研究人员科普他们目前积压的遗传数据和与他们的工作相关的广泛的新遗传数据。HIVbase软件提供的信息能力以前从未被遗传学研究人员使用过。我们新成立的公司，基因约翰逊公司，迅速建立了学术和商业合作伙伴，他们提供了有关产品经济可行性的想法，数据和鼓励。