HIVBaseR 1.0, The Genetic Data Solution

描述(由申请人提供)： 这一第一阶段项目将支持名为HIVbase(R)的软件的开发，该软件将使艾滋病毒研究人员管理和分析基因数据的方式现代化。今天的艾滋病毒调查人员拥有大量用户不友好格式的研究信息、充满错误的电子表格、过时的数据库、包含数千个单独文件的目录，甚至纸质记录。他们需要从这些杂乱无章的信息中提取价值。我们正在开发独特的应用程序，将来自多个来源的艾滋病毒数据整合到一个自动化的高维仓库中，从而解决他们的问题。我们正在开发具有专利价值的蛋白质识别工具，这些工具将消除重复的艾滋病毒序列编辑，并自动创建一个多功能的关系数据系统。我们将为科学家提供一个平台，让他们将用户特定的问题引向海量的基因数据文件，这些搜索可以立即检索数千个序列上特定于站点的遗传属性。艾滋病毒研究市场是巨大的，正在向多个方向增长，迫切需要我们提议的软件。HlVbase的独特之处在于它能够帮助研究人员处理他们目前积压的遗传数据和与他们的努力相关的大量新的遗传数据。HlVbase软件提供的信息能力是基因研究人员以前从未获得过的。我们新成立的公司gene Johnson Inc.迅速建立了学术和商业合作者，他们就该产品的经济可行性提供了想法、数据和鼓励。

DESCRIPTION (provided by applicant): This phase I project will support the development of software -- designated HIVbase (r) -- that will modernize the way HIV researchers manage and analyze genetic data. Today's HIV investigators possess massive amounts of research information in user-hostile formats, error-filled spreadsheets, outdated databases, directories containing thousands of individual files, and even paper records. They need to extract value from this disorganized information. We are solving their problem by developing unique applications for integrating HIV data from multiple sources into an automated high-dimensional warehouse. We are developing patent-worthy protein identification tools that will eliminate repetitious HIV sequence editing and automatically create a multifunctional, relational data system. We will provide a platform for the scientist to direct user-specific questions toward immense files of genetic data, searches that can instantly retrieve site-specific genetic attributes on thousands of sequences. The HIV research market is enormous, growing in multiple directions, and urgently in need of our proposed software. HlVbase is unique in its ability to help researchers cope with both their current backlog of genetic data and extensive new genetic data pertinent to their efforts. The informational power provided by HlVbase software has never before been available to genetic researchers. Our newly founded company, GENE JOHNSON INC., has quickly established academic and commercial collaborators who have provided ideas, data, and encouragement concerning the economic feasibility of the product.