3D Image Guided Endovascular Surgery

3D 图像引导血管内手术

• 批准号: 6622803
• 负责人: Elizabeth Bullitt
• 金额: $ 49.61万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6622803
• 关键词: angiography; bioimaging /biomedical imaging; catheterization; clinical research; digital imaging; human data; image guided surgery /therapy; liver imaging /visualization /scanning; method development; surgery; technology /technique development; three dimensional imaging /topography; video recording system

DESCRIPTION (provided by applicant): Our long-term goal is to combine state-of-the-art, three-dimensional (3D) image guidance with a new method of vascular segmentation and description in order to increase the speed and reduce the risk of difficult endovascular procedures. A specific example of a difficult procedure is transjugular intrahepatic portosystemic shunt formation (TIPS), during which the clinician inserts a needle through a patient's liver in order to connect one venous circulation with another. The target cannot be seen during liver puncture, thus leading to multiple needle passes and high patient risk. Our goal is to provide the clinician accurate, 3D image guidance in order to increase the speed and to decrease the risks of the procedure. Methods include: 1) Segmentation of the vasculature and liver from preoperatively acquired MR or CT data, 2) Intraoperative 3D-2D registration of the segmented 3D vessels with intraoperatively acquired biplane digital subtraction angiograms (DSA), 3) Development of fast, real-time tracking methods to detect changes in the position of the target portal vein resulting from patient respiration or needle pressure on the liver during the procedure, 4) 3D reconstruction of the TIPS needle from biplane views, thus placing the needle within the coordinate system of the 3D vasculature, 5) Integration of information and visualization by means of stereo, head-tracked display, and 6) A four-phase evaluation process. The methods developed under this proposal should be of immediate benefit to TIPS. Moreover, these methods are generally applicable to a wide variety of endovascular procedures, and are thus immediately relevant to the hundreds of thousands of patients with tumors or vascular disease that undergo endovascular treatment each year. Indeed, the methods to be developed under this proposal have the potential to change how endovascular procedures are performed throughout the body.

描述（由申请人提供）：我们的长期目标是结合 最先进的三维 (3D) 图像引导，采用新方法 血管分割和描述，以提高速度并减少 困难的血管内手术的风险。一个具体的例子 困难的手术是经颈静脉肝内门体分流术 (TIPS)，在此期间临床医生将针插入患者的肝脏 为了将一个静脉循环与另一个静脉循环连接起来。目标不能是 在肝穿刺过程中出现，从而导致多次穿刺和高 患者风险。我们的目标是为临床医生提供准确的 3D 图像指导 以提高速度并降低手术风险。 方法包括： 1) 对脉管系统和肝脏进行分割 术前采集的 MR 或 CT 数据，2) 术中 3D-2D 配准 分段 3D 血管与术中获取的双平面数字 减影血管造影 (DSA)，3) 开发快速实时跟踪 检测目标门静脉位置变化的方法 手术过程中患者的呼吸或针头对肝脏的压力， 4) 从双平面视图对 TIPS 针进行 3D 重建，从而将 3D 脉管系统坐标系内的针，5) 积分 通过立体声、头部跟踪显示提供信息和可视化，以及 6) 四阶段评估过程。 根据该提案开发的方法应立即有益于 尖端。而且，这些方法普遍适用于多种领域。 血管内手术，因此与数百个直接相关 数以千计的肿瘤或血管疾病患者接受了血管内治疗 每年治疗。事实上，根据本提案制定的方法 有潜力改变血管内手术的执行方式 遍布全身。