Training in Cellular Mechanisms of CVD

描述（由申请人提供）： 培训计划的目标是创造一个环境，为一代心血管科学家（包括医学博士和博士）提供心血管疾病细胞基础的认识。 这将使学员能够导航从基因组学到复杂系统生理学的连续调查，并使他们能够将这些信息应用于心血管疾病的诊断，治疗和预防。 为了实现这一目标，芝加哥两个主要机构的基础和临床部门都拥有强大的研究和培训记录，他们共同开发了一个综合的翻译培训环境。 培训师经过精心挑选，所有直接研究项目都强调分子和细胞生物学与组织，器官和完整动物生理学的整合。 所有的研究项目都很清楚地表明， 指临床相关的心血管疾病或治疗，包括高血压和肥厚性心脏病、心力衰竭、遗传性肌病、心肌梗死、动脉血管疾病和心律失常。 该计划的重点是无缝的培训环境，学员可以在其中与联合项目的调查团队合作。 博士前候选人（3）将在生理学和生物物理学，药理学部门的研究生学习的第一年后进入该计划，或者（如果参加了MD/博士课程）在医学院的最初几年后。 所有博士前学员将完成的要求，教学和研究，建立了这些 部门 博士后培训生（4）将参加根据他们的兴趣和背景结构的两到三年的计划。 该计划的一个具体目标是确定和培训心脏病专家（一旦他们完成了为期三年的奖学金计划）的基础研究。 这些受训人员将接受类似的培训，不受临床义务的影响，并将提供具体的学术和研究经验，使他们能够竞争入门级研究奖项，并开始独立的研究生涯。 该计划还支持一系列丰富的研讨会和心血管生物学座谈会。

DESCRIPTION (provided by applicant): The objective of the training program is to create an environment that will provide a generation of cardiovascular scientists (both MD and PhD) with an appreciation of the cellular basis of cardiovascular disease. This will allow trainees to navigate the continuum of investigation from genomics to the physiology of complex systems, and will enable them to apply this information to the diagnosis, treatment, and prevention of cardiovascular disease. To meet this objective, both basic and clinical departments of two major institutions in Chicago with strong research and training track records, have come together to develop an integrated translational training environment. Trainers have been carefully selected and all direct research programs that stress the integration of molecular and cellular biology with an appreciation of the physiolology of tissues, organs, and intact animals. All the research programs encompased have very clear reference to clinically relevant cardiovascular diseases or therapy, including hypertensive and hypertrophic heart disease, heart failure, genetic myopathy, myocardial infarction, arteriosclerotic vascular disease, and arhythmogenesis. An emphasis of the program is the seamless training environment within which trainees can collaborate with teams of investigators on joint projects. Pre-doctoral candidates (3) will enter the program after their initial year of graduate studies in either the Departments of Physiology and Biophysics, Pharmacology, or (if enrolled in the MD/PhD program) after their initial years of medical school. All predoctoral trainees will complete the requirements, both didactic and research, established by these Departments. Post-doctoral trainees (4) will participate in two-three year programs that are structured according to their interests and background. A specific goal of the program is to identify and train cardiologists (once they have completed their three-year program of fellowship) in basic research. These trainees will be exposed to a similar period of training that will be unencumbered by clinical obligations and will provide specific academic and research experiences so as to allow them to compete for entry level research awards and to launch independent research careers. The program also supports a rich series of seminars and a colloquium on cardiovascular biology.