CORE--INTERNATIONAL RESEARCH FACILITY

全世界每天有1 200多名儿童死于艾滋病毒感染及其并发症。在几个地理区域，包括东欧、东南亚、东亚和太平洋地区，病例数正在大幅增加。在一个独特的合作，贝勒医学院，与几个罗马尼亚的医疗和科学机构合作，建立了一个儿科艾滋病毒卫生保健专业教育和临床研究计划。拟议的国际研究核心的目的是通过在罗马尼亚建立实验室基础设施，促进艾滋病毒临床和基础研究项目的合作，扩大现有方案的范围，扩大和加强现有方案的活动。国际研究中心的具体目标如下：（1）作为贝勒医学院的科学家与罗马尼亚临床医生和科学家之间的联络人，开展和执行HW合作研究;（2）提供实验室基础设施支持或标本采购，处理，储存和运输;和（3）补充罗马尼亚卫生专业人员和科学教育活动，这些活动是在现有的罗-美儿科艾滋病教育和临床研究计划以及计划中的艾滋病国际培训和研究计划下进行的。 将在Stefan S建立一个设施。布加勒斯特的Nicolau病毒学研究所，用于处理和储存对CFAR研究活动重要的标本。研究所工作人员将协助确定罗马尼亚合作者，并将促进1J.S.罗马尼亚调查员。该研究所将作为罗马尼亚-美国保健研究和保健专业教育活动的协调中心。

Worldwide, over 1200 children die each day from HIV infection and its complications. Large increases in case numbers are being reported in several geographic regions, including Eastern Europe, Southeast Asia, and East Asia and the Pacific. In a unique collaboration, Baylor College of Medicine, in cooperation with several Romanian medical and scientific institutions, has established a program for pediatric HIV health-care professional education and clinical research. The purposes of the proposed International Research Core are to broaden the scope and expand and enhance the activities of the existing prograrn by establishing laboratory infrastructure in Romania to facilitate collaborative HIV clinical and basic research projects. The specific aims of the International Research Core are as follows: (1) to serve as a liaison between scientists at Baylor College of Medicine and Romanian clinicians and scientists in the development, implementation, and execution of HW collaborative research; (2) to provide laboratory mfrastructure support Ior specimen procurement, processing, storage, and shipping; and (3) to complement Romanian health professional and scientific educational activities conducted under the existing Rornanian-American Pediatric AIDS Education and Clinical Research Program and the planned AIDS International Training and Research Prograi:n. A facility will be established at the Stefan S. Nicolau Institute of Virology in Bucharest for the processing and storage of specimens important for CFAR research activities. Institute staff will assist in the identification of Romanian collaborators and will facilitate communication between1J.S. and Romanian investigators. The Institute will serve as the focal point for collaborative Romanian-U.S. HW research and health-care professional educational activities.