Treatment for inner city adolescent girls with CSA-PTSD

患有 CSA-PTSD 的内城少女的治疗

• 批准号: 6732624
• 负责人: Marylene Cloitre
• 金额: $ 21.13万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-04 至 2006-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6732624
• 关键词: adolescence (12-20); behavioral /social science research tag; child abuse; clinical research; clinical trials; cognitive behavior therapy; emotional adjustment; female; human subject; human therapy evaluation; imagery; interpersonal relations; interview; longitudinal human study; patient oriented research; posttraumatic stress disorder; questionnaires; sex abuse; social adjustment; urban area; videotape /videodisc; women' s health

DESCRIPTION (provided by applicant): Adolescent girls who have been sexually abused are known to develop PTSD at substantially high rates and display significant impairments in emotion regulation and social competence. In addition, PTSD in adolescence is a powerful risk factor for substance abuse, suicidality, and revictimization in the teen years. Thus, there is a serious public health need to intervene during this period of heightened risk for multiple negative life outcomes. As yet, there is no effective treatment that addresses the multiple needs of adolescent girls with PTSD. We propose to adapt for adolescent girls an empirically validated, manualized cognitive-behavioral treatment that was developed for an ethnically diverse population of women with PTSD related to childhood abuse. The treatment is composed of two sequential components: a ten-session module of skills training in affective and interpersonal functioning (STAIR) and a six-session module of emotional processing of the traumatic events via imaginal exposure (IE). A five-month open-trial period will be designated to complete and refine the treatment adaptation. Assessment of treatment sessions (by video recordings) and weekly case consultation meetings will be used to monitor and document treatment delivery and make necessary changes to the treatment. This effort will be followed by a preliminary randomized outcome study. A total of 74 adolescent girls with a diagnosis of PTSD will be randomly assigned to either the cognitive-behavioral treatment (STAIR/IE) or to an enhanced treatment as usual (E-TAU) that consists of an identical number of sessions in an unstructured format typical of community treatment for traumatized youth. The efficacy of STAIR/IE and E-TAU will be assessed at post-treatment and at three-month follow-up using measures assessing the three targeted outcomes: 1) emotion management skills, 2) social competence and 3) PTSD symptoms.

描述（由申请人提供）：众所周知，遭受过性虐待的青春期女孩患创伤后应激障碍（PTSD）的几率相当高，并且在情绪调节和社交能力方面表现出明显的损害。此外，青春期的创伤后应激障碍是青少年时期药物滥用、自杀和再次受害的强大危险因素。因此，在多重负面生活结果风险较高的时期，公共卫生部门迫切需要进行干预。迄今为止，还没有有效的治疗方法可以满足患有创伤后应激障碍（PTSD）的少女的多种需求。我们建议为青春期女孩采用一种经过经验验证的手动认知行为治疗方法，该治疗方法是为患有与儿童虐待相关的创伤后应激障碍的不同种族女性群体而开发的。该治疗由两个连续的部分组成：情感和人际功能技能训练的十个会话模块（STAIR）和通过想象暴露对创伤事件进行情感处理的六个会话模块（IE）。将指定为期五个月的开放试验期来完成和完善治疗适应。治疗疗程评估（通过视频记录）和每周病例咨询会议将用于监测和记录治疗实施并对治疗进行必要的改变。这项工作之后将进行初步随机结果研究。总共 74 名被诊断为 PTSD 的青春期女孩将被随机分配接受认知行为治疗 (STAIR/IE) 或照常强化治疗 (E-TAU)，其中包括相同数量的疗程，采用非结构化形式，这是针对受创伤青少年的社区治疗的典型形式。 STAIR/IE 和 E-TAU 的疗效将在治疗后和三个月的随访中使用评估三个目标结果的措施进行评估：1) 情绪管理技能，2) 社交能力和 3) PTSD 症状。