Scleral Buckle Placement in Open-globe Injuries

巩膜带扣在开放性球损伤中的放置

• 批准号: 6759983
• 负责人: JORGE G ARROYO
• 金额: $ 12.56万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-06-01 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6759983
• 关键词: clinical trials; eye disorder diagnosis; eye injury; eye surgery; human subject; human therapy evaluation; implant; longitudinal human study; medical complication; medical implant science; outcomes research; patient oriented research; questionnaires; retina detachment; sclera; statistics /biometry; ultrasonography; visual perception

DESCRIPTION: (Candidate?s Abstract) Although the United States has some of the best medical schools, residencies and fellowships in the world, this medical training is focused on delivering excellent care to patients, rather than developing the research skills necessary to carry out effective clinical investigation. In order for young academic faculty members to take the next step towards becoming independent clinical investigators, further training to obtain these necessary skills is required. The candidate and his mentor, Dr. Louise Ryan, Professor of Biostatists, propose to accomplish this in the following manner: 1) Didactic courses will be taken at the Harvard School of Public Health in clinical epidemiology and biostatistics toward a Masters in Public Health. 2) The candidate will analyze ocular trauma patient data and publish clinical studies in conjunction with Dr. David Hemenway, Director of the Harvard Injury Control Research Center. 3) The candidate will attend weekly clinical research conferences at Harvard Medical School and Harvard School of Public Health. 4) The candidate will participate in the NIH-sponsored Submacular Surgery Trials under the direction of the study chairman, Dr. Nell Bressler. And finally, 5) these clinical research skills will be directly applied towards designing, organizing and obtaining funding for a randomized , prospective multi-center clinical trail entitled, "Prophylatic Scleral Buckle Placement in Posterior Open-globe Injuries." During this final phase, the candidate will work closely with Dr. Evangelos gregoudas, Director of the Retina Service and the Retina research Institute at the Massachusetts Eye 7 Ear Infirmary. The candidate?s long term goal is to obtain independent funding for clinical research studies in the area of ocular trauma and will make a significant contribution to the field of Ophthalmology. The K-23 grant will thus help provide the candidate with a crucial first step towards becoming an inde3pendent clinical researcher and an expert in the field of ocular trauma.

描述：（候选人？s摘要）虽然美国有一些 最好的医学院，住院医生和奖学金在世界上，这个医疗 培训的重点是为患者提供优质的护理，而不是 发展必要的研究技能，以开展有效的临床 调查为了让年轻的学术教师能够参加下一届 逐步成为独立的临床研究者，进一步培训， 获得这些必要的技能是必要的。候选人和他的导师，博士。 路易丝·瑞安，生物统计学教授，建议在 以下方式：1）教学课程将采取在哈佛学院 临床流行病学和生物统计学公共卫生硕士 公共卫生2)候选人将分析眼外伤患者的数据， 与主任大卫·海明威博士联合发表临床研究 哈佛伤害控制研究中心3)候选人将每周参加 临床研究会议在哈佛医学院和哈佛医学院 公共卫生4)候选人将参加NIH主办的 在研究主席Nell博士的指导下进行黄斑下手术试验 布雷斯勒最后，5）这些临床研究技能将直接 应用于设计，组织和获得资金的随机， 前瞻性多中心临床试验，题为“预防性巩膜扣带 后眼球开放性损伤的定位。“在这最后阶段， 候选人将与Evangelos gregoudas博士密切合作，主任 视网膜服务和视网膜研究所在马萨诸塞州眼7耳 医务室候选人？的长期目标是获得独立的资金， 眼外伤领域的临床研究，并将作出一个 对眼科领域的重大贡献。K-23将 从而帮助候选人迈出关键的第一步， 独立的临床研究者和眼外伤领域的专家。