Basic Mechanisms in Virology

描述（由申请人提供）：该计划的目标是在博士前和博士后水平提供高质量的培训，并准备在病毒学的基本机制的研究和教学事业的杰出人士。我们从UAB的30多名病毒学家中选择了那些研究项目专注于病毒学基本机制的人，以发展一个多学科，多部门，由18名研究人员组成的小组，这些研究人员在病毒的分子和结构生物学方面具有公认的专业知识和研究兴趣。这些教师正在进行的研究兴趣包括调查病毒和病毒成分的结构和组装，RNA和DNA疫苗的遗传学和复制，病毒蛋白质的结构-功能关系，以及新型抗病毒剂和疫苗的开发。本提案中的教职员工占据了设备齐全、资金充足的实验室，用于研究的各个阶段。来自生物化学，微生物学，儿科学和医学系的参与教师认为，我们在UAB有一个良好的环境，为现代分子病毒学提供优秀的博士前和博士后培训。博士前学员是从高素质的学生进入名为"细胞和分子生物学（CMB）研究生课程"的多部门计划或高度选择性的医学博士的池的研究的第一年后选择的。博士程序.参加病毒学基本机制计划的博士前和博士后学员的具体要求包括参加病毒学高级课程，期刊俱乐部，每周病毒学研究研讨会以及参加部门研讨会。在相关领域的其他高级课程需要为学生和博士后学员提供。鼓励学员申请个人奖学金和奖项，并指导他们如何撰写研究提案。除了研究活动和课程外，培训计划还包括参加地方，区域和国家科学会议。将通过各种招聘方案在国家一级招聘博士前和博士后学员，并将鼓励招聘少数民族学员。

DESCRIPTION (provided by applicant): The objective of this program is to provide high quality training at the predoctoral and postdoctoral levels and to prepare outstanding individuals for careers in research and teaching in Basic Mechanisms of Virology. We have selected from among the more than 30 virologists at UAB those whose research programs focus on Basic Mechanisms in Virology to develop a multidisciplinary, multi-departmental, group of eighteen investigators with proven expertise and research interests in molecular and structural biology of viruses. The ongoing research interests of these faculty members include investigations of the structure and assembly of viruses and viral components, the genetics and replication of RNA and DNA vaccines, structure-function relationships in viral proteins, and the development of novel antiviral agents and vaccines. The faculty members in this proposal occupy laboratories that are well equipped and well funded for all phases of research. The participating faculty, from the Departments of Biochemistry, Microbiology, Pediatrics, and Medicine, believe that we have at UAB an excellent environment for providing outstanding predoctoral and postdoctoral training in modern molecular Virology. Predoctoral trainees are selected after their first year of study from the pool of highly qualified students entering a multi-departmental program entitled "the Cellular and Molecular Biology (CMB) Graduate Program" or a highly selective M.D./Ph.D. program. Specific requirements for predoctoral and postdoctoral trainees enrolled on the Basic Mechanisms of Virology Program include participation in advanced level courses in virology, a journal club, the weekly Virology research seminars as well as attendance at Departmental seminars. Additional advanced courses in related fields are required for students and available to postdoctoral trainees. Trainees are encouraged to apply for individual fellowships and awards, and are instructed in how to write research proposals. In addition to research activities and courses, the training program includes participation in local, regional, and national scientific meetings. Recruitment of both predoctoral and postdoctoral trainees will be at the national level through a variety of recruitment programs and will encourage recruitment of minority participants.