Interpersonal Functioning in Borderline Personality

描述（由申请人提供）：本申请是MH 56888的修改后的竞争性延续申请，现在的标题为“边缘人格中的人际功能”。“总体目标是更详细地描述边缘型人格障碍（BPD）患者的人际功能，并比以前做的更具临床意义。将检查BPD中人际功能的概念层次结构，范围从长期的相关性模式到即时的人际评估，并将测试这些测量方法的结构和预测有效性。第一个具体目标是使用多种措施来表征BPD患者的成人依恋风格。第二个具体目标是进行详细的评估，这些患者的人际功能领域的浪漫关系，友谊，和工作使用国家的最先进的采访，修订的成人人格功能评估（RAPFA）。第三个具体目标是证明RAPFA确定的依恋类型和相关模式与实际的日常人际功能有关;为此，将使用改编自罗切斯特互动记录的社会互动日记。在最详细的分析水平，第四个具体的目标是进行评估的BPD患者的社会认知使用的范式评估偏见的感知中立的人脸。研究将在三组（每组N = 50）中进行：BPD患者和两个对照组-回避型人格障碍（AVPD）患者和无PD患者，即，只有第一轴情绪或焦虑症患者。所有患者将在入院时进行评估，并前瞻性随访6个月。这些目标的实现将是重要的，不仅为建立这些人际变量在BPD的结构和预测效度，但也为促进发展的代表谁患有这种疾病的患者的改进治疗。识别人际风险因素将有助于实现长期目标，不仅要了解这些患者，而且要将这些知识用于基于科学的治疗，以改善他们的生活。

DESCRIPTION (provided by applicant): This submission is an amended competing continuation application for MH56888, now titled "Interpersonal Functioning in Borderline Personality." The overall goal is to characterize the interpersonal functioning of patients with borderline personality disorder (BPD) in greater detail and with greater clinical relevance than has been done previously. A conceptual hierarchy of interpersonal functioning in BPD will be examined, ranging from long-term patterns of relatedness to moment-to-moment interpersonal appraisals, and the construct and predictive validity of these measures will be tested. The first specific aim is to characterize the adult attachment styles of BPD patients using multiple measures. The second specific aim is to undertake a detailed assessment of the interpersonal functioning of these patients in the areas of romantic relationships, friendships, and work using a state-of-the-art interview, the Revised Adult Personality Functioning Assessment (RAPFA). The third specific aim is to document that both attachment styles and patterns of relatedness identified with the RAPFA are associated with actual day-to-day interpersonal functioning; for this purpose, a Social Interaction Diary, adapted from the Rochester Interaction Record, will be used. At the most detailed level of analysis, the fourth specific aim is to undertake an assessment of social cognition in BPD patients using a paradigm evaluating biases in the perception of neutral human faces. The research will be conducted with three groups (N = 50 in each group): Patients with BPD and two comparison groups-patients with avoidant personality disorder (AVPD) and patients with no PD, i.e., those with an Axis I mood or anxiety disorder only. All patients will be assessed at intake and followed prospectively for six months. The accomplishment of these aims will be important not only for establishing the construct and predictive validity of these interpersonal variables in BPD but also for promoting the development of improved treatments on behalf of patients who suffer from this disorder. Identification of interpersonal risk factors will help achieve the long-term goal of not only knowing these patients well but also using this knowledge in sc ce-based therapies to improve their lives.