Parkinson Disease Neuroprotection Clinical Trial

描述（由申请人提供）：NINDS寻求建立临床试验中心，在开发和测试神经保护治疗新方法方面进行合作。佛蒙特大学医学院（UVM/COM）、达特茅斯希区柯克医学中心（DHMC）和缅因州神经病学（缅因州医学中心）的神经病学项目将共同合作，以建立北方新英格兰临床试验中心（NNE-CTC）。具体而言，NNE-CTC的目标是：招募和随访早期帕金森病（PD）受试者进行PD神经保护的随机临床试验;提供高质量的临床评估、数据录入和管理，并满足实验性神经治疗的所有法规要求;在中心和整个项目的结构范围内，发展新的介入治疗方法和评估策略;为了将我们的临床中心完全融入NINDS赞助的神经保护试验项目的运作中，并与试验的各个方面充分合作。除了这些具体目标，NNE的总体目标-CTC将为北方新英格兰和纽约北部的公民带来参与神经退行性疾病不断发展的治疗的机会。

DESCRIPTION (provided by applicant): The NINDS seeks to establish Clinical Trial Sites that will collaborate and cooperate in the development and testing of new approaches to neuroprotection therapy. The Neurology programs at the University of Vermont College of Medicine (UVM/COM), the Dartmouth Hitchcock Medical Center (DHMC), and Maine Neurology (Maine Medical Center) will work together in order to establish a Northern New England Clinical Trials Center (NNE-CTC). Specifically, the aims of the NNE-CTC are:To recruit and follow subjects with early Parkinson's disease (PD) for a randomized clinical trial of Neuroprotection in PD;To provide high quality clinical assessment, and data entry and management, and to meet all regulatory statutes outlined for experimental neurotherapeutics;To evolve new approaches to interventional therapy and assessment strategies as permitted within the structure of the Center and overall project;To fully integrate our Clinical Center into the operation of the NINDS sponsored Neuroprotection Trial program and to fully cooperate with all aspects of the trial.In addition to these specific aims, an overall goal of the NNE-CTC is to bring opportunities for the citizens of Northern New England and Upstate New York to participate in the evolving therapies for neurodegenerative disorders.