Micro-environment Glasses as a Treatment for CVS

描述(申请人提供)计算机视觉综合症(CVS)是指与使用计算机相关的一组眼睛问题，大约四分之三的计算机用户患有这种疾病。保守估计表明，目前有超过20亿美元用于CVS的检查和特殊眼镜治疗。CVS最常见的症状包括：眼睛疲劳或眼睛疲劳、眼睛干燥、眼睛灼热、对光敏感和视力模糊。非眼部症状包括头痛、肩部、颈部或背部疼痛。尽管症状多种多样，但它们可能与三种潜在的病理生理原因有关，并可细分为三种： 1)眼表机制 2)调节机构 3)眼外机制 关于这种疾病的诊断方面的知识基金有很大的缺口。在短期内，我们计划将重点放在作为CVS原因之一的眼表疾病类别上，确定与这种综合征相关的临床情况，并开发一种解决这一原因的治疗方法。在第一阶段，我们建议： 通过观察有症状的受试者眼表异常的发生率来临床定义CVS，并将其与年龄和性别匹配的无症状对照人群进行比较 开发专门的微环境眼镜来对抗CVS症状 微环境眼镜在有症状人群和对照人群中的疗效研究 批判性评估CVS微环境玻璃作为商业产品的可行性 采用统计方法和主观问卷调查相结合的方法。

DESCRIPTION (provided by applicant) Computer Vision Syndrome (CVS) refers to a collection of eye problems associated with computer use, and about three-quarters of computer users have it. Conservative estimates indicate that over $2 billion is currently spent on examinations and special eyewear for CVS treatment. The most common symptoms of CVS include: eyestrain or eye fatigue, dry eyes, burning eyes, sensitivity to light, and blurred vision. Non-ocular symptoms include headaches, pain in the shoulders, neck, or back. As diverse as the symptoms are, they may be related and can be subdivided into to three potential pathophysiological causes: 1) Ocular Surface Mechanisms 2) Accommodative Mechanisms 3) Extra-Ocular Mechanisms There is a significant gap in the fund of knowledge regarding the diagnosis of this disease. In the near-term, we plan to focus on the ocular surface category of disorders as a cause of CVS, identify clinical conditions associated with this syndrome and develop a treatment that addresses this cause. In phase 1, we propose to: Clinically define CVS by observing the incidence of ocular surface abnormalities in symptomatic subjects and compare them with an age and sex matched non-symptomatic control population Develop specialized micro-environment glasses to combat CVS symptoms Study the efficacy of micro-environment glasses in symptomatic and control populations Critically evaluate viability of CVS micro-environment glasses as a commercial product using both statistical methods and subjective questionnaires.