Fusing and damping osseointegrated implants

背景尽管存在未知的长期伤口护理和感染问题，但在许多方面，用于下肢的骨整合(OI)植入物是解决插座装配问题的理想解决方案。然而，目前仍有一些重大的机械问题完全没有得到解决。长期的机械效应也是未知的。这些机械效应主要与机械失效有关(骨折、种植体松动或连接器失效)，以及潜在的疼痛或加速的骨关节炎(包括骨痛、关节痛、下腰痛)，可能是由于冲击载荷从地板通过类骨假体和硬性OI种植体直接传递到骨骼而造成的。目前还没有定制的工程解决方案。研究问题OI假体是否可以与OI假体一起使用，并为使用者的舒适性、生理过载保护、OI假体失败和骨折提供减震保护？PHD的目标是开发一种设计工具箱，以优化膝盖以上截肢者骨集成植入物和外部假体之间复杂的、有时相互冲突的固定约束。本PHD的一个详细目标是彻底调查OI种植体和残留骨之间的相互作用，因为大多数力学问题都是从这一区域产生的。

BackgroundDespite the unknown long-term wound care and infection issues, osseointegrated (OI) implants for the lower limb are, in many ways, an ideal solution for socket fitting problems. There remain, however, significant mechanical issues that are currently totally unaddressed. The long-term mechanical effects are also not known. These mechanical effects are mainly related to mechanical failure (bone fracture, implant loosening, or connector failure) and, potentially,pain or accelerated osteoarthritis (including bone pain, joint pain, lower back pain) likely due to shock loading transmitted from the floor through therigid prosthesis and rigid OI implant directlyto the bone. There are currently no bespoke engineered solutions. Research ProblemCan 'standard' prostheses be used with OI implants and provide damping and shock protection for user comfort, physiological overload protection, and OI implant failure and bone fracture?PhD aimsThe aim of the PhD is to develop a design toolbox to optimise the complex set of, sometimes conflicting, constraints on the fixation between an osseointegrated implant and the external prosthesis for an above knee amputee. One of the detailed objectives of this PhD is to thoroughly investigate the interaction between the OI implant and the residual bone as most mechanical issues arise from this area.