Optimal Design of Sustainable Capsules for Targeted Delivery of Active

用于活性成分靶向输送的可持续胶囊的优化设计

• 批准号: 2351064
• 金额: --
• 依托单位: University of Birmingham
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2351064
• 关键词: Optimal; Design; Sustainable; Capsules; Targeted

Tailoring the structural properties of sustainable capsules containing active materials is of critical importance to maximize stability and performance in consumer product formulations. To ensure optimal capsule design, we desire: (i) The ability to modify the surface properties of capsules with different coating materials to boost the performance of the encapsulated active, maximizing targeted delivery.(ii) The ability to tailor the structure of the capsules to improve stability of the encapsulated material in the finished product throughout storage, supply chain, etc. (iii) The ability to identify and reapply new methods to optimize wall surface and composition enhancing capsule stability and performance in 'real world' consumer applications.(iv) The ability to predict and measure the 'trigger properties' when changing capsule surface structure and properties as well as wall thickness, capsule size, etc. The initial focus will be to tailor the structure and surface of sustainable capsules to archive superior stability and performance in consumer product formulations used in laundry machine washing processes.

定制含有活性材料的可持续胶囊的结构特性对于最大限度地提高消费品配方的稳定性和性能至关重要。为了确保最佳的胶囊设计，我们希望：（i）能够用不同的包衣材料改变胶囊的表面性质，以提高包封的活性物质的性能，最大化靶向递送。(ii)定制胶囊的结构以提高最终产品中的包封材料在整个储存、供应链等中的稳定性的能力。（iii）鉴定和再应用新方法以优化壁表面和组合物的能力，所述组合物增强胶囊在“真实的世界”消费者应用中的稳定性和性能。(iv)当改变胶囊表面结构和性质以及壁厚、胶囊尺寸等时，能够预测和测量“触发性质”。最初的重点将是定制可持续胶囊的结构和表面，以在洗衣机洗涤过程中使用的消费品配方中获得上级稳定性和性能。