Imaging of Regional Myocardial Perfusion and Function

局部心肌灌注和功能的成像

• 批准号: 6801197
• 负责人: SANJIV KAUL
• 金额: $ 11.63万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6801197
• 关键词: Imaging; Regional; Myocardial; Perfusion; Function

DESCRIPTION (provided by applicant): Cardiovascular disease is the major cause of morbidity and mortality in the United States. It is anticipated that by 2020 it will become the major cause of death in the world, surpassing infectious disease for the first time. At the same time, increasing longevity in the developed world is contributing to a greater prevalence of this disease despite major advances in its prevention and treatment. The sheer number of patients with different forms of cardiovascular disease makes it logistically impossible to use invasive procedures to make a diagnosis. The need for noninvasive methods to detect early disease has therefore never been as crucial. Technical advances in cardiovascular imaging have resulted in their increased use over the years. Nuclear cardiology and echocardiography are now mature technologies that are commonly used in clinical practice. Magnetic Resonance Imaging (MRI) as well as helical CT has also started to play a role in the clinical assessment of cardiovascular disease. Nonetheless, the number of physicians and other technical personnel who have in-depth expertise in these fields is sadly lacking. In most cardiology training programs, increased emphasis on invasive procedures results in the production of trainees with a very superficial knowledge of noninvasive imaging. Even if a trainee spends a substantial amount of time in noninvasive laboratories, they are likely to develop expertise in only one of the imaging modalities. The University of Virginia is one of a handful of centers in the U.S. that have high-level expertise in all forms of cardiac imaging as well as a track record of training physicians in these modalities. Many of these physicians are currently full time in academics and are running their own experimental or clinical laboratories. The purpose of this grant proposal is to develop a research training program that will provide comprehensive training in all three modalities: nuclear cardiology, echocardiography, and MRI with particular emphasis placed on coronary artery disease, which is the primary research interest of all the faculty who will participate in the training program. Equal emphasis will be placed on the technical aspects of imaging as well as on physiology and pathophysiology. The ultimate aim is to train individuals who will become tomorrow's academic leaders in cardiovascular imaging.

描述（由申请人提供）： 心血管疾病是美国发病率和死亡率的主要原因。预计到2020年，它将成为世界上首次超越传染病的主要死亡原因。同时，尽管其预防和治疗取得了重大进展，但发达国家的寿命日益增长正在导致这种疾病的更大率。具有不同形式的心血管疾病的患者数量庞大，因此在逻辑上不可能使用侵入性手术进行诊断。因此，对检测早期疾病的非侵入性方法的需求从来都不是至关重要的。 多年来，心血管成像的技术进步导致它们的使用增加。 核心脏病学和超声心动图现在是临床实践中通常使用的成熟技术。磁共振成像（MRI）以及螺旋CT也开始在心血管疾病的临床评估中发挥作用。尽管如此，在这些领域中具有深入专业知识的医师和其他技术人员的数量仍然是可悲的。在大多数心脏病学培训计划中，对侵入性程序的越来越重视导致受训者的生产具有非常肤浅的无创成像知识。即使受训者在非侵入性实验室花费大量时间，他们也可能仅在其中一种成像方式中发展专业知识。 弗吉尼亚大学是美国少数几个中心之一，在各种形式的心脏成像方面都具有高级专业知识，并且是这些方式中培训医师的记录。这些医生中的许多人目前都在学术界全职，并且正在运营自己的实验或临床实验室。 这项赠款提案的目的是制定一项研究培训计划，该计划将提供所有三种方式的全面培训：核心脏病学，超声心动图和MRI，特别重视冠状动脉疾病，这是所有将参加培训计划的所有教师的主要研究利益。同等的重点将放在成像以及生理学和病理生理学的技术方面。最终目标是培训将成为明天在心血管成像中的学术领导者的个人。