Core--Developmental Facility

宾夕法尼亚- cfar发展核心项目的主要目标是通过为试点项目提供资金来源，促进宾夕法尼亚大学、费城儿童医院和Wistar研究所的艾滋病和艾滋病毒相关研究。发展核心基金将支持新兴艾滋病研究领域的短期（1年）项目，包括招募新研究人员的新研究、将注意力转向AII3S的知名研究人员的研究，以及开展与以往工作有重大不同的艾滋病/艾滋病研究人员的研究。在过去的供资期间，我们总共资助了18个项目，其范围从病毒和病毒蛋白的分子分析，通过潜在的候选疫苗开发，到对一些非洲社会性信息传播的社会学分析。这些试点项目的很大一部分已经转化为完全资助的NIH拨款。我们建议在CFAR的第6-10年每年资助5个项目，并增加一个新的资助类别，专门用于跨学科和/或转化研究项目。

The major goal of the Penn-CFAR Developmental Core is the promotion of AIDS and HIV-related research at the University of Pennsylvania, the Children's Hospital of Philadelphia, and the Wistar Institute by providing a source of funding for pilot projects. The Developmental Core will support short term (1 year) projects in emerging areas of HIV research, including new research related to the recruitment of new investigators, research by established investigators who are turning their attention to AII3S, and research by AIDS/HIV investigators who are undertaking studies that represent a significant departure from their previous work. During the past funding period, we funded a total of 18 projects ranging in scope from molecular analysis of viruses and virus proteins, through the potential development of vaccine candidates, to sociological analysis of the transmission of sexual information in some African societies. A significant proportion of these pilot projects have been converted into fully funded NIH grants. We are proposing to fund 5 projects each year in years 6-10 of this CFAR, adding a new grant category devoted exclusively to interdisciplinary and/or translational research projects.