CORE--Clinical Resource

核心--临床资源

• 批准号: 6841594
• 负责人: JOHN R. WINGARD
• 金额: $ 4.43万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6841594
• 关键词: Aspergillus; Candida albicans; biomedical facility; candidiasis; human tissue; serum; tissue resource /registry; virulence

A clinical resource core will be created to support the four projects. Serum, tissue, and clinical fungal isolates will be prospectively collected from a diverse group of patients with different types of Candida and Aspergillus infections. These specimens will be stored, characterized with clinical data, and a database for retrieval will be created for use by investigators of the four projects to characterize determinants of fungal virulence that are turned on in the course of various types of infection and pertinent host responses. Specimens will be made available to outside investigators to complement the program's objectives. Administrative support to the program project will also be provided.

将创建一个临床资源核心来支持这四个项目。将从患有不同类型念珠菌和曲霉菌感染的不同患者群体中前瞻性地收集血清、组织和临床真菌分离株。这些样本将被存储，并用临床数据进行表征，并将创建一个检索数据库，供这四个项目的研究人员使用，以表征在各种类型的感染和相关宿主反应过程中开启的真菌毒力的决定因素。样本将提供给外部研究人员以补充该计划的目标。还将为该计划项目提供行政支持。