DIABETES - ENDORINOLOGY RESEARCH CENTER

描述(直接从应用程序中获取) 马萨诸塞大学医学院糖尿病内分泌学 研究中心(DERC)成立于1982年，其目标是加强和 促进糖尿病及相关代谢和内分泌疾病的研究。 在其17年的活动中，它汇集了一个不断扩大的、 由近60名独立成员科学家组成的多学科小组，新 研究人员，以及代表几乎所有学科的研究实习生 医学和基础科学。DERC已经成功地培育了一种浓缩 计划以及小规模和大规模协作，包括几个 跨学科计划项目。最近，DERC正式宣布 将杰克逊实验室的工作人员科学家整合到其研究基地 和管理结构。马萨诸塞州联邦已经 回报是对跨学科项目和资金的支持 对研究设施的投资。DERC支持的研究范围 活动范围非常广泛，从基础分子生物学到临床 糖尿病患者的耐受性移植。然而，所有成员， 在研究方面有共同的兴趣，这是理解 糖尿病的发病机制，是向新的治疗方法发展的方向 战略，或侧重于相关的代谢和内分泌紊乱。这个 DERC旨在维护和增强已有基础设施 展示了其催化创新研究的能力。DERC的重点 仍在其研究中心，现在将扩大到五个，以使 可获得所需的尖端技术。这些核心提供了资金基础 和临床研究人员有机会利用资源 并有效地扩大其研究项目的范围。这些措施包括 细胞科学和流动显微荧光法，转基因动物，形态-电子 显微镜-细胞成像、多肽合成和蛋白质组学核心。一个 行政核心监督中心的运作、试点和可行性 项目，以及浓缩项目。 马萨诸塞大学医学院DERC的目标一直是 将继续促进糖尿病及相关课题的研究。 具体地说，DERC将1)促进跨学科互动，2) 有效提高糖尿病研究的生产力和效率 通过核心设施，3)通过试点和 可行性奖，4)促进对青年调查人员的培训 糖尿病相关研究，以及5)创造一个机构环境， 加强对糖尿病或相关代谢和内分泌的研究 精神错乱。

DESCRIPTION (Taken directly from the application) The University of Massachusetts Medical School (UMMS) Diabetes Endocrinology Research Center (DERC) was established in 1982 with the goal of enhancing and promoting research in diabetes and related metabolic and endocrine disorders. During its 17 years of activity, it has brought together an expanding, multi-disciplinary group of nearly 60 independent member scientists, new investigators, and research trainees who represent nearly all disciplines of Medicine and the Basic Sciences. The DERC has fostered a successful enrichment program and both small and large-scale collaborations, including several interdisciplinary Program Projects. Most recently the DERC has formally integrated Staff Scientists from the Jackson Laboratory into its research base and administrative structure. The Commonwealth of Massachusetts has reciprocated with support for interdisciplinary programs and capital investments in research facilities. The scope of DERC-supported research activities is very broad, ranging from basic molecular biology to clinical tolerance-based transplantation in diabetic patients. All members, however, share a common interest in research that is fundamental to understanding diabetes pathogenesis, is directed towards the development of new treatment strategies, or is focused on related metabolic and endocrine disorders. The DERC is designed to maintain and to enhance an infrastructure that has already demonstrated its ability to catalyze innovative research. The focus of the DERC remains at its Research Cores, which will now be expanded to five to make available required cutting edge technologies. The Cores provide funded basic and clinical investigators with the opportunity to utilize resources efficiently and to expand the scope of their research programs. These include Cell Science and Flow Microfluorometry, Transgenic Animals, Morphology-Electron Microscopy-Cell Imaging, Peptide Synthesis, and Proteomics Cores. An Administrative Core oversees the operation of the Center, Pilot and Feasibility Projects, and the Enrichment Programs. The goal of the University of Massachusetts Medical School DERC has been and will continue to be to facilitate research in diabetes and related subjects. Specifically, the DERC will 1) stimulate interdisciplinary interactions, 2) efficiently enhance the productivity and efficiency of diabetes research through Core facilities, 3) bootstrap new research efforts through pilot and feasibility awards, 4) promote the training of young investigators in diabetes-related research, and 5) create an institution environment that amplifies research efforts in diabetes or related metabolic and endocrine disorders.