课题基金 / 基金详情

DIABETES - ENDORINOLOGY RESEARCH CENTER

DIABETES - ENDORINOLOGY RESEARCH CENTER
糖尿病 - 内分泌学研究中心
批准号:
6634892
负责人:
ALDO A ROSSINI
金额:
$117.56万
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-06-01 至 2005-03-31

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中文摘要
翻译
描述(直接取自应用程序) 马萨诸塞州大学医学院(UMMS)糖尿病内分泌学 研究中心(DERC)成立于1982年,其目标是提高和 促进对糖尿病及相关代谢和内分泌紊乱的研究。 在其17年的活动中,它汇集了一个不断扩大的, 由近60名独立成员科学家组成的多学科小组,新 研究人员和研究实习生谁代表几乎所有学科的 医学和基础科学。DERC成功地培养了 计划和小型和大型合作,包括几个 跨学科项目。最近,DERC正式 将杰克逊实验室的科学家纳入其研究基地 和行政结构。马萨诸塞州已经 回报为对跨学科项目和资本的支持 投资研究设施。DERC支持的研究范围 活动非常广泛,从基础分子生物学到临床 糖尿病患者的耐受性移植。然而,所有成员, 在研究方面有着共同的兴趣, 糖尿病发病机制,是针对新的治疗方法的发展 战略,或专注于相关的代谢和内分泌疾病。的 DERC的目的是维护和加强基础设施, 证明了其催化创新研究的能力。DERC的重点 仍然在其研究核心,现在将扩大到五个,使 提供所需的尖端技术。核心提供资助的基本 和临床研究者有机会利用 提高效率,扩大其研究计划的范围。这些包括 细胞科学和流式显微荧光测定法,转基因动物,形态学-电子 显微镜-细胞成像,肽合成和蛋白质组学核心。一个 行政核心监督中心的运作,试点和可行性 项目和丰富计划。 马萨诸塞州医学院DERC的目标是, 将继续促进糖尿病及相关学科的研究。 具体来说,DERC将1)促进跨学科的互动,2) 有效提高糖尿病研究的生产力和效率 通过核心设施,3)引导新的研究工作, 可行性奖,4)促进年轻调查员的培训, 糖尿病相关研究,5)创造一个机构环境, 加强糖尿病或相关代谢和内分泌的研究工作 紊乱
英文摘要
DESCRIPTION (Taken directly from the application) The University of Massachusetts Medical School (UMMS) Diabetes Endocrinology Research Center (DERC) was established in 1982 with the goal of enhancing and promoting research in diabetes and related metabolic and endocrine disorders. During its 17 years of activity, it has brought together an expanding, multi-disciplinary group of nearly 60 independent member scientists, new investigators, and research trainees who represent nearly all disciplines of Medicine and the Basic Sciences. The DERC has fostered a successful enrichment program and both small and large-scale collaborations, including several interdisciplinary Program Projects. Most recently the DERC has formally integrated Staff Scientists from the Jackson Laboratory into its research base and administrative structure. The Commonwealth of Massachusetts has reciprocated with support for interdisciplinary programs and capital investments in research facilities. The scope of DERC-supported research activities is very broad, ranging from basic molecular biology to clinical tolerance-based transplantation in diabetic patients. All members, however, share a common interest in research that is fundamental to understanding diabetes pathogenesis, is directed towards the development of new treatment strategies, or is focused on related metabolic and endocrine disorders. The DERC is designed to maintain and to enhance an infrastructure that has already demonstrated its ability to catalyze innovative research. The focus of the DERC remains at its Research Cores, which will now be expanded to five to make available required cutting edge technologies. The Cores provide funded basic and clinical investigators with the opportunity to utilize resources efficiently and to expand the scope of their research programs. These include Cell Science and Flow Microfluorometry, Transgenic Animals, Morphology-Electron Microscopy-Cell Imaging, Peptide Synthesis, and Proteomics Cores. An Administrative Core oversees the operation of the Center, Pilot and Feasibility Projects, and the Enrichment Programs. The goal of the University of Massachusetts Medical School DERC has been and will continue to be to facilitate research in diabetes and related subjects. Specifically, the DERC will 1) stimulate interdisciplinary interactions, 2) efficiently enhance the productivity and efficiency of diabetes research through Core facilities, 3) bootstrap new research efforts through pilot and feasibility awards, 4) promote the training of young investigators in diabetes-related research, and 5) create an institution environment that amplifies research efforts in diabetes or related metabolic and endocrine disorders.
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Administrative Core
Adaptive immunity in virus-induced diabetes in BBDR rats
Project 1: Induction of Immunological Tolerance to Islet Allografts
Adaptive immunity in virus-induced diabetes in BBDR rats
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